Enhanced Flexible Mold Lifetime for Roll‐to‐Roll Scaled‐Up Manufacturing of Adhesive Complex Microstructures
Bioinspired Microstructured Adhesives with Facile and Fast Switchability for Part Manipulation in Dry and Wet Conditions
Smart Materials for manipulation and actuation of small-scale structures
3D nanofabrication of various materials for advanced multifunctional microrobots
Liquid Crystal Mesophase of Supercooled Liquid Gallium And Eutectic Gallium–Indium
Machine Learning-Based Pull-off and Shear Optimal Adhesive Microstructures
Information entropy to detect order in self-organizing systems
Individual and collective manipulation of multifunctional bimodal droplets in three dimensions
Microrobot collectives with reconfigurable morphologies and functions
Self-organization in heterogeneous and non-reciprocal regime
Biomimetic Emulsion Systems
Giant Unilamellar Vesicles for Designing Cell-like Microrobots
Bioinspired self-assembled colloidal collectives drifting in three dimensions underwater
Photodynamic Ocular Drug Delivery System with Optical Coherence Tomography Oriented Microscale Robots
Retinal diseases are the most common reasons for irreversible blindness, and their incidence increases each year. Retinal diseases, such as diabetic retinopathy, macular degeneration, retinal vein occlusion, and non-infectious uveitis, require intraocular drug delivery for treatment. Unfortunately, drug delivery to the posterior part of the eye is complex, ineffective, and complicated because of the anatomical barrier of the ocular surface, retina-blood barrier, and rheological structure of the vitreous. While topical and systemic administration of the drugs could not achieve sufficient concentrations, intraocular injections create repeated traumas and infections in the diseased eye. Novel treatment options also come with their problems. For example, commercial intravitreal implants for dexamethasone release lead to increased intraocular pressure, which also worsens ocular pathologies like open-angle glaucoma. Most of the nanoparticles produced for the retinal delivery of corticosteroids also cannot access the retina because of vitreous humor and the inner membrane of the retina. The project aims to develop an intelligent retinal drug delivery system by combining novel material, biomedical, and micro-robotic technologies. For this purpose, we build covalent organic frame work based microrobots that can actuate with optical stimulation.
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