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Miscellaneous 2020

Snapshot whole brain CEST MRI at 3T with 3D-EPI

{CEST MRI provides metabolite-based contrasts but often suffers from poor volume coverage or spatial resolution. We optimized and included a snapshot 3D-EPI readout and propose a suitable post-processing pipeline to generate CEST contrast in the whole brain at clinical B0\textequals3T. It is shown that CEST MRI with 1.8mm isotropic nominal resolution at a field of view of 256x224x156mm\mbox{$^3$} is feasible within 4.3s per presaturation frequency offset. The approach is adaptable for any presaturation scheme. Exemplarily low power saturation was performed and fitted Lorentzian amplitudes gave a coefficient of variation \textless8.5\textpercent across three healthy subjects.}

Author(s): Mueller, S and Stirnberg, R and Akbey, S and Ehses, P and Scheffler, K and Stöcker, T and Zaiss, M
Book Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
Year: 2020
Bibtex Type: Miscellaneous (misc)
Electronic Archiving: grant_archive

BibTex 

@misc{item_3248063,
  title = {{Snapshot whole brain CEST MRI at 3T with 3D-EPI}},
  booktitle = {{2020 ISMRM \& SMRT Virtual Conference \& Exhibition}},
  abstract = {{CEST MRI provides metabolite-based contrasts but often suffers from poor volume coverage or spatial resolution. We optimized and included a snapshot 3D-EPI readout and propose a suitable post-processing pipeline to generate CEST contrast in the whole brain at clinical B0\textequals3T. It is shown that CEST MRI with 1.8mm isotropic nominal resolution at a field of view of 256x224x156mm\mbox{$^3$} is feasible within 4.3s per presaturation frequency offset. The approach is adaptable for any presaturation scheme. Exemplarily low power saturation was performed and fitted Lorentzian amplitudes gave a coefficient of variation \textless8.5\textpercent across three healthy subjects.}},
  year = {2020},
  slug = {item_3248063},
  author = {Mueller, S and Stirnberg, R and Akbey, S and Ehses, P and Scheffler, K and St\"ocker, T and Zaiss, M}
}