Miscellaneous 2019

Relaxation corrected and Sequence-dependent Macromolecule Baseline Model

{In short echo time spectroscopy sequences macromolecular signals may strongly influence the quantification of metabolite spectra they underlay. In this work we present a method for simulating a MM basis set that is tailored toward chosen sequences and sequence parameters with the aim to improve the accuracy of metabolite measurements in vivo. We show that utilizing a simulated macromolecule basis set while considering the relaxation behavior of individual macromolecular resonances can produce metabolite quantification results of similar quality to that of a dedicatedly measured MM basis set when applied to the same spectra of interest.}

Author(s): Wright, A and Murali Manohar, S and Henning, A
Book Title: ISMRM 27th Annual Meeting & Exhibition
Year: 2019
Bibtex Type: Miscellaneous (misc)
Electronic Archiving: grant_archive

BibTex

@misc{item_3054634,
  title = {{Relaxation corrected and Sequence-dependent Macromolecule Baseline Model}},
  booktitle = {{ISMRM 27th Annual Meeting \& Exhibition}},
  abstract = {{In short echo time spectroscopy sequences macromolecular signals may strongly influence the quantification of metabolite spectra they underlay. In this work we present a method for simulating a MM basis set that is tailored toward chosen sequences and sequence parameters with the aim to improve the accuracy of metabolite measurements in vivo. We show that utilizing a simulated macromolecule basis set while considering the relaxation behavior of individual macromolecular resonances can produce metabolite quantification results of similar quality to that of a dedicatedly measured MM basis set when applied to the same spectra of interest.}},
  year = {2019},
  slug = {item_3054634},
  author = {Wright, A and Murali Manohar, S and Henning, A}
}