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Miscellaneous 2020

Towards intravascular BOLD signal characterization in balanced SSFP experiments of human blood at high to ultra-high fields

{To fully understand the neurovascular fingerprint observed in BOLD experiments, extravascular and intravascular contributions have to be identified separately. Balanced steady-state free precession (bSSFP) imaging has demonstrated the ability for distortion-free fMRI with high microvascular sensitivity. However, the underlying intravascular contribution to BOLD bSSFP is not yet entirely known as literature R2 relaxation rates do not reflect the apparent diffusion-related R2 decrease in blood with shorter bSSFP refocusing intervals (TRs). This work thus focuses on characterizing the oxygen sensitivity of bSSFP in blood samples at high to ultra-high fields by means of passband signal differences and intrinsic R2 estimation.}

Author(s): Pérez-Rodas, M and Schulz, H and Pohmann, R and Scheffler, K and Heule, R
Book Title: 2020 ISMRM & SMRT Virtual Conference & Exhibition
Pages: 415
Year: 2020
Bibtex Type: Miscellaneous (misc)
Electronic Archiving: grant_archive

BibTex 

@misc{item_3248025,
  title = {{Towards intravascular BOLD signal characterization in balanced SSFP experiments of human blood at high to ultra-high fields}},
  booktitle = {{2020 ISMRM \& SMRT Virtual Conference \& Exhibition}},
  abstract = {{To fully understand the neurovascular fingerprint observed in BOLD experiments, extravascular and intravascular contributions have to be identified separately. Balanced steady-state free precession (bSSFP) imaging has demonstrated the ability for distortion-free fMRI with high microvascular sensitivity. However, the underlying intravascular contribution to BOLD bSSFP is not yet entirely known as literature R2 relaxation rates do not reflect the apparent diffusion-related R2 decrease in blood with shorter bSSFP refocusing intervals (TRs). This work thus focuses on characterizing the oxygen sensitivity of bSSFP in blood samples at high to ultra-high fields by means of passband signal differences and intrinsic R2 estimation.}},
  pages = {415},
  year = {2020},
  slug = {item_3248025},
  author = {P\'erez-Rodas, M and Schulz, H and Pohmann, R and Scheffler, K and Heule, R}
}