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Empirical Inference Conference Paper Gaussian Processes in Reinforcement Learning Rasmussen, C., Kuss, M. In Advances in Neural Information Processing Systems 16, Advances in Neural Information Processing Systems 16, 751-759, (Editors: Thrun, S., L. K. Saul, B. Schölkopf), MIT Press, Cambridge, MA, USA, Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
We exploit some useful properties of Gaussian process (GP) regression models for reinforcement learning in continuous state spaces and discrete time. We demonstrate how the GP model allows evaluation of the value function in closed form. The resulting policy iteration algorithm is demonstrated on a simple problem with a two dimensional state space. Further, we speculate that the intrinsic ability of GP models to characterise distributions of functions would allow the method to capture entire distributions over future values instead of merely their expectation, which has traditionally been the focus of much of reinforcement learning.
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Empirical Inference Conference Paper Image Construction by Linear Programming Tsuda, K., Rätsch, G. In Advances in Neural Information Processing Systems 16, Advances in Neural Information Processing Systems 16, 57-64, (Editors: Thrun, S., L.K. Saul, B. Schölkopf), MIT Press, Cambridge, MA, USA, Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
A common way of image denoising is to project a noisy image to the subspace of admissible images made for instance by PCA. However, a major drawback of this method is that all pixels are updated by the projection, even when only a few pixels are corrupted by noise or occlusion. We propose a new method to identify the noisy pixels by 1-norm penalization and update the identified pixels only. The identification and updating of noisy pixels are formulated as one linear program which can be solved efficiently. Especially, one can apply the ν-trick to directly specify the fraction of pixels to be reconstructed. Moreover, we extend the linear program to be able to exploit prior knowledge that occlusions often appear in contiguous blocks (e.g. sunglasses on faces). The basic idea is to penalize boundary points and interior points of the occluded area differently. We are able to show the ν-property also for this extended LP leading a method which is easy to use. Experimental results impressively demonstrate the power of our approach.
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Empirical Inference Conference Paper Insights from Machine Learning Applied to Human Visual Classification Graf, A., Wichmann, F. In Advances in Neural Information Processing Systems 16, Advances in Neural Information Processing Systems 16, 905-912, (Editors: Thrun, S., L. Saul, B. Schölkopf), MIT Press, Cambridge, MA, USA, Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
We attempt to understand visual classification in humans using both psychophysical and machine learning techniques. Frontal views of human faces were used for a gender classification task. Human subjects classified the faces and their gender judgment, reaction time and confidence rating were recorded. Several hyperplane learning algorithms were used on the same classification task using the Principal Components of the texture and flowfield representation of the faces. The classification performance of the learning algorithms was estimated using the face database with the true gender of the faces as labels, and also with the gender estimated by the subjects. We then correlated the human responses to the distance of the stimuli to the separating hyperplane of the learning algorithms. Our results suggest that human classification can be modeled by some hyperplane algorithms in the feature space we used. For classification, the brain needs more processing for stimuli close to that hyperplane than for those further away.
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Empirical Inference Conference Paper Learning to Find Pre-Images Bakir, G., Weston, J., Schölkopf, B. In Advances in Neural Information Processing Systems, Advances in Neural Information Processing Systems 16, 449-456, (Editors: S Thrun and LK Saul and B Schölkopf), MIT Press, Cambridge, MA, USA, 17th Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
We consider the problem of reconstructing patterns from a feature map. Learning algorithms using kernels to operate in a reproducing kernel Hilbert space (RKHS) express their solutions in terms of input points mapped into the RKHS. We introduce a technique based on kernel principal component analysis and regression to reconstruct corresponding patterns in the input space (aka pre-images) and review its performance in several applications requiring the construction of pre-images. The introduced technique avoids difficult and/or unstable numerical optimization, is easy to implement and, unlike previous methods, permits the computation of pre-images in discrete input spaces.
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Empirical Inference Conference Paper Learning with Local and Global Consistency Zhou, D., Bousquet, O., Lal, T., Weston, J., Schölkopf, B. In Advances in Neural Information Processing Systems, Advances in Neural Information Processing Systems 16, 321-328, (Editors: S Thrun and LK Saul and B Schölkopf), MIT Press, Cambridge, MA, USA, 17th Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
We consider the general problem of learning from labeled and unlabeled data, which is often called semi-supervised learning or transductive inference. A principled approach to semi-supervised learning is to design a classifying function which is sufficiently smooth with respect to the intrinsic structure collectively revealed by known labeled and unlabeled points. We present a simple algorithm to obtain such a smooth solution. Our method yields encouraging experimental results on a number of classification problems and demonstrates effective use of unlabeled data.
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Empirical Inference Conference Paper Measure Based Regularization Bousquet, O., Chapelle, O., Hein, M. In Advances in Neural Information Processing Systems, Advances in Neural Information Processing Systems 16, 1221-1228, (Editors: Thrun, S., L. Saul, B. Schölkopf), MIT Press, Cambridge, MA, USA, Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
We address in this paper the question of how the knowledge of the marginal distribution $P(x)$ can be incorporated in a learning algorithm. We suggest three theoretical methods for taking into account this distribution for regularization and provide links to existing graph-based semi-supervised learning algorithms. We also propose practical implementations.
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Empirical Inference Conference Paper PAC-Bayesian Generic Chaining Audibert, J., Bousquet, O. In Advances in Neural Information Processing Systems 16, Advances in Neural Information Processing Systems 16, 1125-1132 , (Editors: Thrun, S., L.K. Saul, B. Schölkopf), MIT Press, Cambridge, MA, USA, Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
There exist many different generalization error bounds for classification. Each of these bounds contains an improvement over the others for certain situations. Our goal is to combine these different improvements into a single bound. In particular we combine the PAC-Bayes approach introduced by McAllester, which is interesting for averaging classifiers, with the optimal union bound provided by the generic chaining technique developed by Fernique and Talagrand. This combination is quite natural since the generic chaining is based on the notion of majorizing measures, which can be considered as priors on the set of classifiers, and such priors also arise in the PAC-bayesian setting.
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Empirical Inference Conference Paper Prediction on Spike Data Using Kernel Algorithms Eichhorn, J., Tolias, A., Zien, A., Kuss, M., Rasmussen, C., Weston, J., Logothetis, N., Schölkopf, B. In Advances in Neural Information Processing Systems 16: Proceedings of the 2003 Conference, Advances in Neural Information Processing Systems 16, 1367-1374, (Editors: S Thrun and LK Saul and B Schölkopf), MIT Press, Cambridge, MA, USA, 17th Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
We report and compare the performance of different learning algorithms based on data from cortical recordings. The task is to predict the orientation of visual stimuli from the activity of a population of simultaneously recorded neurons. We compare several ways of improving the coding of the input (i.e., the spike data) as well as of the output (i.e., the orientation), and report the results obtained using different kernel algorithms.
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Empirical Inference Conference Paper Ranking on Data Manifolds Zhou, D., Weston, J., Gretton, A., Bousquet, O., Schölkopf, B. In Advances in Neural Information Processing Systems, Advances in neural information processing systems 16, 169-176, (Editors: S Thrun and L Saul and B Schölkopf), MIT Press, Cambridge, MA, USA, 17th Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
The Google search engine has enjoyed a huge success with its web page ranking algorithm, which exploits global, rather than local, hyperlink structure of the web using random walks. Here we propose a simple universal ranking algorithm for data lying in the Euclidean space, such as text or image data. The core idea of our method is to rank the data with respect to the intrinsic manifold structure collectively revealed by a great amount of data. Encouraging experimental results from synthetic, image, and text data illustrate the validity of our method.
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Empirical Inference Conference Paper Semi-Supervised Protein Classification using Cluster Kernels Weston, J., Leslie, C., Zhou, D., Elisseeff, A., Noble, W. In Advances in Neural Information Processing Systems, Advances in Neural Information Processing Systems 16, 595-602, (Editors: Thrun, S., L.K. Saul, B. Schölkopf), MIT Press, Cambridge, MA, USA, Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
A key issue in supervised protein classification is the representation of input sequences of amino acids. Recent work using string kernels for protein data has achieved state-of-the-art classification performance. However, such representations are based only on labeled data --- examples with known 3D structures, organized into structural classes --- while in practice, unlabeled data is far more plentiful. In this work, we develop simple and scalable cluster kernel techniques for incorporating unlabeled data into the representation of protein sequences. We show that our methods greatly improve the classification performance of string kernels and outperform standard approaches for using unlabeled data, such as adding close homologs of the positive examples to the training data. We achieve equal or superior performance to previously presented cluster kernel methods while achieving far greater computational efficiency.
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Empirical Inference Article Support Vector Channel Selection in BCI Lal, T., Schröder, M., Hinterberger, T., Weston, J., Bogdan, M., Birbaumer, N., Schölkopf, B. IEEE Transactions on Biomedical Engineering, 51(6):1003-1010, June 2004
Designing a Brain Computer Interface (BCI) system one can choose from a variety of features that may be useful for classifying brain activity during a mental task. For the special case of classifying EEG signals we propose the usage of the state of the art feature selection algorithms Recursive Feature Elimination and Zero-Norm Optimization which are based on the training of Support Vector Machines (SVM). These algorithms can provide more accurate solutions than standard filter methods for feature selection. We adapt the methods for the purpose of selecting EEG channels. For a motor imagery paradigm we show that the number of used channels can be reduced significantly without increasing the classification error. The resulting best channels agree well with the expected underlying cortical activity patterns during the mental tasks. Furthermore we show how time dependent task specific information can be visualized.
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Empirical Inference Conference Paper Warped Gaussian Processes Snelson, E., Rasmussen, C., Ghahramani, Z. In Advances in Neural Information Processing Systems 16, Advances in Neural Information Processing Systems 16, 337-344, (Editors: Thrun, S., L.K. Saul, B. Schölkopf), MIT Press, Cambridge, MA, USA, Seventeenth Annual Conference on Neural Information Processing Systems (NIPS 2003), June 2004
We generalise the Gaussian process (GP) framework for regression by learning a nonlinear transformation of the GP outputs. This allows for non-Gaussian processes and non-Gaussian noise. The learning algorithm chooses a nonlinear transformation such that transformed data is well-modelled by a GP. This can be seen as including a preprocessing transformation as an integral part of the probabilistic modelling problem, rather than as an ad-hoc step. We demonstrate on several real regression problems that learning the transformation can lead to significantly better performance than using a regular GP, or a GP with a fixed transformation.
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Empirical Inference Book Chapter Distributed Command Execution Stark, S., Berlin, M. In BSD Hacks: 100 industrial-strength tips & tools, 152-152, (Editors: Lavigne, Dru), O’Reilly, Beijing, May 2004
Often you want to execute a command not only on one computer, but on several at once. For example, you might want to report the current statistics on a group of managed servers or update all of your web servers at once.
BibTeX

Empirical Inference Conference Paper Kernel Hebbian Algorithm for single-frame super-resolution Kim, K., Franz, M., Schölkopf, B. In Statistical Learning in Computer Vision (SLCV 2004), Computer Vision - ECCV 2004, LNCS vol. 3024, 135-149, (Editors: A Leonardis and H Bischof), Springer, Berlin, Germany, 8th European Conference on Computer Vision (ECCV 2004), May 2004
This paper presents a method for single-frame image super-resolution using an unsupervised learning technique. The required prior knowledge about the high-resolution images is obtained from Kernel Principal Component Analysis (KPCA). The original form of KPCA, however, can be only applied to strongly restricted image classes due to the limited number of training examples that can be processed. We therefore propose a new iterative method for performing KPCA, the {em Kernel Hebbian Algorithm}. By kernelizing the Generalized Hebbian Algorithm, one can iteratively estimate the Kernel Principal Components with only linear order memory complexity. The resulting super-resolution algorithm shows a comparable performance to the existing supervised methods on images containing faces and natural scenes.
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Empirical Inference Article A Compression Approach to Support Vector Model Selection von Luxburg, U., Bousquet, O., Schölkopf, B. Journal of Machine Learning Research, 5:293-323, April 2004
In this paper we investigate connections between statistical learning theory and data compression on the basis of support vector machine (SVM) model selection. Inspired by several generalization bounds we construct "compression coefficients" for SVMs which measure the amount by which the training labels can be compressed by a code built from the separating hyperplane. The main idea is to relate the coding precision to geometrical concepts such as the width of the margin or the shape of the data in the feature space. The so derived compression coefficients combine well known quantities such as the radius-margin term R^2/rho^2, the eigenvalues of the kernel matrix, and the number of support vectors. To test whether they are useful in practice we ran model selection experiments on benchmark data sets. As a result we found that compression coefficients can fairly accurately predict the parameters for which the test error is minimized.
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Empirical Inference Article cDNA-Microarray Technology in Cartilage Research - Functional Genomics of Osteoarthritis [in German] Aigner, T., Finger, F., Zien, A., Bartnik, E. Zeitschrift f{\"u}r Orthop{\"a}die und ihre Grenzgebiete, 142(2):241-247, April 2004
Functional genomics represents a new challenging approach in order to analyze complex diseases such as osteoarthritis on a molecular level. The characterization of the molecular changes of the cartilage cells, the chondrocytes, enables a better understanding of the pathomechanisms of the disease. In particular, the identification and characterization of new target molecules for therapeutic intervention is of interest. Also, potential molecular markers for diagnosis and monitoring of osteoarthritis contribute to a more appropriate patient management. The DNA-microarray technology complements (but does not replace) biochemical and biological research in new disease-relevant genes. Large-scale functional genomics will identify molecular networks such as yet identified players in the anabolic-catabolic balance of articular cartilage as well as disease-relevant intracellular signaling cascades so far rather unknown in articular chondrocytes. However, at the moment it is also important to recognize the limitations of the microarray technology in order to avoid over-interpretation of the results. This might lead to misleading results and prevent to a significant extent a proper use of the potential of this technology in the field of osteoarthritis.
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Empirical Inference Technical Report Kamerakalibrierung und Tiefenschätzung: Ein Vergleich von klassischer Bündelblockausgleichung und statistischen Lernalgorithmen Sinz, F. Wilhelm-Schickard-Institut für Informatik, Universität Tübingen, Tübingen, Germany, March 2004
Die Arbeit verleicht zwei Herangehensweisen an das Problem der Sch{\"a}tzung der r{\"a}umliche Position eines Punktes aus den Bildkoordinaten in zwei verschiedenen Kameras. Die klassische Methode der B{\"u}ndelblockausgleichung modelliert zwei Einzelkameras und sch{\"a}tzt deren {\"a}ußere und innere Orientierung mit einer iterativen Kalibrationsmethode, deren Konvergenz sehr stark von guten Startwerten abh{\"a}ngt. Die Tiefensch{\"a}tzung eines Punkts geschieht durch die Invertierung von drei der insgesamt vier Projektionsgleichungen der Einzalkameramodelle. Die zweite Methode benutzt Kernel Ridge Regression und Support Vector Regression, um direkt eine Abbildung von den Bild- auf die Raumkoordinaten zu lernen. Die Resultate zeigen, daß der Ansatz mit maschinellem Lernen, neben einer erheblichen Vereinfachung des Kalibrationsprozesses, zu h{\"o}heren Positionsgenaugikeiten f{\"u}hren kann.
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Empirical Inference Poster EEG Channel Selection for Brain Computer Interface Systems Based on Support Vector Methods Schröder, M., Lal, T., Bogdan, M., Schölkopf, B. 7:50, (Editors: Bülthoff, H.H., H.A. Mallot, R. Ulrich and F.A. Wichmann), 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
A Brain Computer Interface (BCI) system allows the direct interpretation of brain activity patterns (e.g. EEG signals) by a computer. Typical BCI applications comprise spelling aids or environmental control systems supporting paralyzed patients that have lost motor control completely. The design of an EEG based BCI system requires good answers for the problem of selecting useful features during the performance of a mental task as well as for the problem of classifying these features. For the special case of choosing appropriate EEG channels from several available channels, we propose the application of variants of the Support Vector Machine (SVM) for both problems. Although these algorithms do not rely on prior knowledge they can provide more accurate solutions than standard lter methods [1] for feature selection which usually incorporate prior knowledge about neural activity patterns during the performed mental tasks. For judging the importance of features we introduce a new relevance measure and apply it to EEG channels. Although we base the relevance measure for this purpose on the previously introduced algorithms, it does in general not depend on specic algorithms but can be derived using arbitrary combinations of feature selectors and classifiers.
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Empirical Inference Poster Efficient Approximations for Support Vector Classiers Kienzle, W., Franz, M. 7:68, 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
In face detection, support vector machines (SVM) and neural networks (NN) have been shown to outperform most other classication methods. While both approaches are learning-based, there are distinct advantages and drawbacks to each method: NNs are difcult to design and train but can lead to very small and efcient classiers. In comparison, SVM model selection and training is rather straightforward, and, more importantly, guaranteed to converge to a globally optimal (in the sense of training errors) solution. Unfortunately, SVM classiers tend to have large representations which are inappropriate for time-critical image processing applications. In this work, we examine various existing and new methods for simplifying support vector decision rules. Our goal is to obtain efcient classiers (as with NNs) while keeping the numerical and statistical advantages of SVMs. For a given SVM solution, we compute a cascade of approximations with increasing complexities. Each classier is tuned so that the detection rate is near 100%. At run-time, the rst (simplest) detector is evaluated on the whole image. Then, any subsequent classier is applied only to those positions that have been classied as positive throughout all previous stages. The false positive rate at the end equals that of the last (i.e. most complex) detector. In contrast, since many image positions are discarded by lower-complexity classiers, the average computation time per patch decreases signicantly compared to the time needed for evaluating the highest-complexity classier alone.
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Empirical Inference Poster Efficient Approximations for Support Vector Classifiers Kienzle, W., Franz, M. 7:68, 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
In face detection, support vector machines (SVM) and neural networks (NN) have been shown to outperform most other classication methods. While both approaches are learning-based, there are distinct advantages and drawbacks to each method: NNs are difcult to design and train but can lead to very small and efcient classiers. In comparison, SVM model selection and training is rather straightforward, and, more importantly, guaranteed to converge to a globally optimal (in the sense of training errors) solution. Unfortunately, SVM classiers tend to have large representations which are inappropriate for time-critical image processing applications. In this work, we examine various existing and new methods for simplifying support vector decision rules. Our goal is to obtain efcient classiers (as with NNs) while keeping the numerical and statistical advantages of SVMs. For a given SVM solution, we compute a cascade of approximations with increasing complexities. Each classier is tuned so that the detection rate is near 100%. At run-time, the rst (simplest) detector is evaluated on the whole image. Then, any subsequent classier is applied only to those positions that have been classied as positive throughout all previous stages. The false positive rate at the end equals that of the last (i.e. most complex) detector. In contrast, since many image positions are discarded by lower-complexity classiers, the average computation time per patch decreases signicantly compared to the time needed for evaluating the highest-complexity classier alone.
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Empirical Inference Poster Human Classification Behaviour Revisited by Machine Learning Graf, A., Wichmann, F., Bülthoff, H., Schölkopf, B. 7:134, (Editors: Bülthoff, H.H., H.A. Mallot, R. Ulrich and F.A. Wichmann), 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
We attempt to understand visual classication in humans using both psychophysical and machine learning techniques. Frontal views of human faces were used for a gender classication task. Human subjects classied the faces and their gender judgment, reaction time (RT) and condence rating (CR) were recorded for each face. RTs are longer for incorrect answers than for correct ones, high CRs are correlated with low classication errors and RTs decrease as the CRs increase. This results suggest that patterns difcult to classify need more computation by the brain than patterns easy to classify. Hyperplane learning algorithms such as Support Vector Machines (SVM), Relevance Vector Machines (RVM), Prototype learners (Prot) and K-means learners (Kmean) were used on the same classication task using the Principal Components of the texture and oweld representation of the faces. The classication performance of the learning algorithms was estimated using the face database with the true gender of the faces as labels, and also with the gender estimated by the subjects. Kmean yield a classication performance close to humans while SVM and RVM are much better. This surprising behaviour may be due to the fact that humans are trained on real faces during their lifetime while they were here tested on articial ones, while the algorithms were trained and tested on the same set of stimuli. We then correlated the human responses to the distance of the stimuli to the separating hyperplane (SH) of the learning algorithms. On the whole stimuli far from the SH are classied more accurately, faster and with higher condence than those near to the SH if we pool data across all our subjects and stimuli. We also nd three noteworthy results. First, SVMs and RVMs can learn to classify faces using the subjects' labels but perform much better when using the true labels. Second, correlating the average response of humans (classication error, RT or CR) with the distance to the SH on a face-by-face basis using Spearman's rank correlation coefcients shows that RVMs recreate human performance most closely in every respect. Third, the mean-of-class prototype, its popularity in neuroscience notwithstanding, is the least human-like classier in all cases examined.
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Empirical Inference Poster Learning Depth Sinz, F., Franz, M. 69, (Editors: H.H.Bülthoff, H.A.Mallot, R.Ulrich,F.A.Wichmann), 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
The depth of a point in space can be estimated by observing its image position from two different viewpoints. The classical approach to stereo vision calculates depth from the two projection equations which together form a stereocamera model. An unavoidable preparatory work for this solution is a calibration procedure, i.e., estimating the external (position and orientation) and internal (focal length, lens distortions etc.) parameters of each camera from a set of points with known spatial position and their corresponding image positions. This is normally done by iteratively linearizing the single camera models and reestimating their parameters according to the error on the known datapoints. The advantage of the classical method is the maximal usage of prior knowledge about the underlying physical processes and the explicit estimation of meaningful model parameters such as focal length or camera position in space. However, the approach neglects the nonlinear nature of the problem such that the results critically depend on the choice of the initial values for the parameters. In this study, we approach the depth estimation problem from a different point of view by applying generic machine learning algorithms to learn the mapping from image coordinates to spatial position. These algorithms do not require any domain knowledge and are able to learn nonlinear functions by mapping the inputs into a higher-dimensional space. Compared to classical calibration, machine learning methods give a direct solution to the depth estimation problem which means that the values of the stereocamera parameters cannot be extracted from the learned mapping. On the poster, we compare the performance of classical camera calibration to that of different machine learning algorithms such as kernel ridge regression, gaussian processes and support vector regression. Our results indicate that generic learning approaches can lead to higher depth accuracies than classical calibration although no domain knowledge is used.
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Empirical Inference Poster Selective Attention to Auditory Stimuli: A Brain-Computer Interface Paradigm Hill, N., Lal, T., Schröder, M., Hinterberger, T., Birbaumer, N., Schölkopf, B. 7:102, (Editors: Bülthoff, H.H., H.A. Mallot, R. Ulrich and F.A. Wichmann), 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
During the last 20 years several paradigms for Brain Computer Interfaces have been proposed— see [1] for a recent review. They can be divided into (a) stimulus-driven paradigms, using e.g. event-related potentials or visual evoked potentials from an EEG signal, and (b) patient-driven paradigms such as those that use premotor potentials correlated with imagined action, or slow cortical potentials (e.g. [2]). Our aim is to develop a stimulus-driven paradigm that is applicable in practice to patients. Due to the unreliability of visual perception in “locked-in” patients in the later stages of disorders such as Amyotrophic Lateral Sclerosis, we concentrate on the auditory modality. Speci- cally, we look for the effects, in the EEG signal, of selective attention to one of two concurrent auditory stimulus streams, exploiting the increased activation to attended stimuli that is seen under some circumstances [3]. We present the results of our preliminary experiments on normal subjects. On each of 400 trials, two repetitive stimuli (sequences of drum-beats or other pulsed stimuli) could be heard simultaneously. The two stimuli were distinguishable from one another by their acoustic properties, by their source location (one from a speaker to the left of the subject, the other from the right), and by their differing periodicities. A visual cue preceded the stimulus by 500 msec, indicating which of the two stimuli to attend to, and the subject was instructed to count the beats in the attended stimulus stream. There were up to 6 beats of each stimulus: with equal probability on each trial, all 6 were played, or the fourth was omitted, or the fth was omitted. The 40-channel EEG signals were analyzed ofine to reconstruct which of the streams was attended on each trial. A linear Support Vector Machine [4] was trained on a random subset of the data and tested on the remainder. Results are compared from two types of pre-processing of the signal: for each stimulus stream, (a) EEG signals at the stream's beat periodicity are emphasized, or (b) EEG signals following beats are contrasted with those following missing beats. Both forms of pre-processing show promising results, i.e. that selective attention to one or the other auditory stream yields signals that are classiable signicantly above chance performance. In particular, the second pre-processing was found to be robust to reduction in the number of features used for classication (cf. [5]), helping us to eliminate noise.
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Empirical Inference Poster Texture and Haptic Cues in Slant Discrimination: Measuring the Effect of Texture Type Rosas, P., Wichmann, F., Ernst, M., Wagemans, J. 7:165, (Editors: Bülthoff, H. H., H. A. Mallot, R. Ulrich, F. A. Wichmann), 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
In a number of models of depth cue combination the depth percept is constructed via a weighted average combination of independent depth estimations. The inuence of each cue in such average depends on the reliability of the source of information [1,5]. In particular, Ernst and Banks (2002) formulate such combination as that of the minimum variance unbiased estimator that can be constructed from the available cues. We have observed systematic differences in slant discrimination performance of human observers when different types of textures were used as cue to slant [4]. If the depth percept behaves as described above, our measurements of the slopes of the psychometric functions provide the predicted weights for the texture cue for the ranked texture types. However, the results for slant discrimination obtained when combining these texture types with object motion results are difcult to reconcile with the minimum variance unbiased estimator model [3]. This apparent failure of such model might be explained by the existence of a coupling of texture and motion, violating the assumption of independence of cues. Hillis, Ernst, Banks, and Landy (2002) [2] have shown that while for between-modality combination the human visual system has access to the single-cue information, for withinmodality combination (visual cues) the single-cue information is lost. This suggests a coupling between visual cues and independence between visual and haptic cues. Then, in the present study we combined the different texture types with haptic information in a slant discrimination task, to test whether in the between-modality condition these cues are combined as predicted by an unbiased, minimum variance estimator model. The measured weights for the cues were consistent with a combination rule sensitive to the reliability of the sources of information, but did not match the predictions of a statistically optimal combination.
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Empirical Inference Poster m-Alternative-Forced-Choice: Improving the Efficiency of the Method of Constant Stimuli Jäkel, F., Hill, J., Wichmann, F. 7:118, 7th T{\"u}bingen Perception Conference (TWK 2004), February 2004
We explored several ways to improve the efficiency of measuring psychometric functions without resorting to adaptive procedures. a) The number m of alternatives in an m-alternative-forced-choice (m-AFC) task improves the efficiency of the method of constant stimuli. b) When alternatives are presented simultaneously on different positions on a screen rather than sequentially time can be saved and memory load for the subject can be reduced. c) A touch-screen can further help to make the experimental procedure more intuitive. We tested these ideas in the measurement of contrast sensitivity and compared them to results obtained by sequential presentation in two-interval-forced-choice (2-IFC). Qualitatively all methods (m-AFC and 2-IFC) recovered the characterictic shape of the contrast sensitivity function in three subjects. The m-AFC paradigm only took about 60% of the time of the 2-IFC task. We tried m=2,4,8 and found 4-AFC to give the best model fits and 2-AFC to have the least bias.
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Empirical Inference Article Experimentally optimal v in support vector regression for different noise models and parameter settings Chalimourda, A., Schölkopf, B., Smola, A. Neural Networks, 17(1):127-141, January 2004
In Support Vector (SV) regression, a parameter ν controls the number of Support Vectors and the number of points that come to lie outside of the so-called var epsilon-insensitive tube. For various noise models and SV parameter settings, we experimentally determine the values of ν that lead to the lowest generalization error. We find good agreement with the values that had previously been predicted by a theoretical argument based on the asymptotic efficiency of a simplified model of SV regression. As a side effect of the experiments, valuable information about the generalization behavior of the remaining SVM parameters and their dependencies is gained. The experimental findings are valid even for complex ‘real-world’ data sets. Based on our results on the role of the ν-SVM parameters, we discuss various model selection methods.
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Empirical Inference Talk Introduction to Category Theory Bousquet, O. Internal Seminar, January 2004
A brief introduction to the general idea behind category theory with some basic definitions and examples. A perspective on higher dimensional categories is given.
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Empirical Inference Talk Learning from Labeled and Unlabeled Data: Semi-supervised Learning and Ranking Zhou, D. January 2004
We consider the general problem of learning from labeled and unlabeled data, which is often called semi-supervised learning or transductive inference. A principled approach to semi-supervised learning is to design a classifying function which is sufficiently smooth with respect to the intrinsic structure collectively revealed by known labeled and unlabeled points. We present a simple algorithm to obtain such a smooth solution. Our method yields encouraging experimental results on a number of classification problems and demonstrates effective use of unlabeled data.
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Empirical Inference Conference Paper A New Variational Framework for Rigid-Body Alignment Kato, T., Tsuda, K., Tomii, K., Asai, K. In Joint IAPR International Workshops on Syntactical and Structural Pattern Recognition (SSPR 2004) and Statistical Pattern Recognition (SPR 2004), 171-179, (Editors: Fred, A.,T. Caelli, R.P.W. Duin, A. Campilho and D. de Ridder), Joint IAPR International Workshops on Syntactical and Structural Pattern Recognition (SSPR 2004) and Statistical Pattern Recognition (SPR 2004), 2004 PDF BibTeX

Empirical Inference Book Chapter A Primer on Kernel Methods Vert, J., Tsuda, K., Schölkopf, B. In Kernel Methods in Computational Biology, 35-70, (Editors: B Schölkopf and K Tsuda and JP Vert), MIT Press, Cambridge, MA, USA, 2004 PDF BibTeX

Empirical Inference Conference Paper A Regularization Framework for Learningfrom Graph Data Zhou, D., Schölkopf, B. In ICML Workshop on Statistical Relational Learning and Its Connections to Other Fields, 132-137, ICML, 2004
The data in many real-world problems can be thought of as a graph, such as the web, co-author networks, and biological networks. We propose a general regularization framework on graphs, which is applicable to the classification, ranking, and link prediction problems. We also show that the method can be explained as lazy random walks. We evaluate the method on a number of experiments.
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Empirical Inference Article A Tutorial on Support Vector Regression Smola, A., Schölkopf, B. Statistics and Computing, 14(3):199-222, 2004 Web BibTeX

Empirical Inference Conference Paper A kernel view of the dimensionality reduction of manifolds Ham, J., Lee, D., Mika, S., Schölkopf, B. In Proceedings of the Twenty-First International Conference on Machine Learning, 369-376, (Editors: CE Brodley), ACM, New York, NY, USA, ICML, 2004, also appeared as MPI-TR 110
We interpret several well-known algorithms for dimensionality reduction of manifolds as kernel methods. Isomap, graph Laplacian eigenmap, and locally linear embedding (LLE) all utilize local neighborhood information to construct a global embedding of the manifold. We show how all three algorithms can be described as kernel PCA on specially constructed Gram matrices, and illustrate the similarities and differences between the algorithms with representative examples.
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Empirical Inference Book Chapter A primer on molecular biology Zien, A. In 3-34, (Editors: Schoelkopf, B., K. Tsuda and J. P. Vert), MIT Press, Cambridge, MA, USA, 2004
Modern molecular biology provides a rich source of challenging machine learning problems. This tutorial chapter aims to provide the necessary biological background knowledge required to communicate with biologists and to understand and properly formalize a number of most interesting problems in this application domain. The largest part of the chapter (its first section) is devoted to the cell as the basic unit of life. Four aspects of cells are reviewed in sequence: (1) the molecules that cells make use of (above all, proteins, RNA, and DNA); (2) the spatial organization of cells (``compartmentalization''); (3) the way cells produce proteins (``protein expression''); and (4) cellular communication and evolution (of cells and organisms). In the second section, an overview is provided of the most frequent measurement technologies, data types, and data sources. Finally, important open problems in the analysis of these data (bioinformatics challenges) are briefly outlined.
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Empirical Inference Article Asymptotic Properties of the Fisher Kernel Tsuda, K., Akaho, S., Kawanabe, M., Müller, K. Neural Computation, 16(1):115-137, 2004 PDF BibTeX

Empirical Inference Article Bayesian analysis of the Scatterometer Wind Retrieval Inverse Problem: Some New Approaches Cornford, D., Csato, L., Evans, D., Opper, M. Journal of the Royal Statistical Society B, 66:1-17, 3, 2004
The retrieval of wind vectors from satellite scatterometer observations is a non-linear inverse problem.A common approach to solving inverse problems is to adopt a Bayesian framework and to infer the posterior distribution of the parameters of interest given the observations by using a likelihood model relating the observations to the parameters, and a prior distribution over the parameters.We show how Gaussian process priors can be used efficiently with a variety of likelihood models, using local forward (observation) models and direct inverse models for the scatterometer.We present an enhanced Markov chain Monte Carlo method to sample from the resulting multimodal posterior distribution.We go on to show how the computational complexity of the inference can be controlled by using a sparse, sequential Bayes algorithm for estimation with Gaussian processes.This helps to overcome the most serious barrier to the use of probabilistic, Gaussian process methods in remote sensing inverse problems, which is the prohibitively large size of the data sets.We contrast the sampling results with the approximations that are found by using the sparse, sequential Bayes algorithm.
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Empirical Inference Technical Report Behaviour and Convergence of the Constrained Covariance Gretton, A., Smola, A., Bousquet, O., Herbrich, R., Schölkopf, B., Logothetis, N. (130), MPI for Biological Cybernetics, 2004
We discuss reproducing kernel Hilbert space (RKHS)-based measures of statistical dependence, with emphasis on constrained covariance (COCO), a novel criterion to test dependence of random variables. We show that COCO is a test for independence if and only if the associated RKHSs are universal. That said, no independence test exists that can distinguish dependent and independent random variables in all circumstances. Dependent random variables can result in a COCO which is arbitrarily close to zero when the source densities are highly non-smooth, which can make dependence hard to detect empirically. All current kernel-based independence tests share this behaviour. Finally, we demonstrate exponential convergence between the population and empirical COCO, which implies that COCO does not suffer from slow learning rates when used as a dependence test.
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Empirical Inference Ph.D. Thesis Classification and Feature Extraction in Man and Machine Graf, A. Biologische Kybernetik, University of Tübingen, Germany, 2004, online publication BibTeX

Empirical Inference Poster Classification and Memory Behaviour of Man Revisited by Machine Graf, A., Wichmann, F., Bülthoff, H., Schölkopf, B. CSHL Meeting on Computational & Systems Neuroscience (COSYNE), 2004 BibTeX

Empirical Inference Conference Paper Clustering Protein Sequence and Structure Space with Infinite Gaussian Mixture Models Dubey, A., Hwang, S., Rangel, C., Rasmussen, C., Ghahramani, Z., Wild, D. In Pacific Symposium on Biocomputing 2004; Vol. 9, 399-410, World Scientific Publishing, Singapore, Pacific Symposium on Biocomputing, 2004
We describe a novel approach to the problem of automatically clustering protein sequences and discovering protein families, subfamilies etc., based on the thoery of infinite Gaussian mixture models. This method allows the data itself to dictate how many mixture components are required to model it, and provides a measure of the probability that two proteins belong to the same cluster. We illustrate our methods with application to three data sets: globin sequences, globin sequences with known tree-dimensional structures and G-pretein coupled receptor sequences. The consistency of the clusters indicate that that our methods is producing biologically meaningful results, which provide a very good indication of the underlying families and subfamilies. With the inclusion of secondary structure and residue solvent accessibility information, we obtain a classification of sequences of known structure which reflects and extends their SCOP classifications. A supplementary web site containing larger versions of the figures is available at http://public.kgi.edu/~wild/PSB04
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Empirical Inference Book Chapter Concentration Inequalities Boucheron, S., Lugosi, G., Bousquet, O. In Lecture Notes in Artificial Intelligence 3176:208-240, (Editors: Bousquet, O., U. von Luxburg and G. Rätsch), Springer, Heidelberg, Germany, 2004 PDF BibTeX

Empirical Inference Technical Report Confidence Sets for Ratios: A Purely Geometric Approach To Fieller’s Theorem von Luxburg, U., Franz, V. (133), Max Planck Institute for Biological Cybernetics, 2004
We present a simple, geometric method to construct Fieller's exact confidence sets for ratios of jointly normally distributed random variables. Contrary to previous geometric approaches in the literature, our method is valid in the general case where both sample mean and covariance are unknown. Moreover, not only the construction but also its proof are purely geometric and elementary, thus giving intuition into the nature of the confidence sets.
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Empirical Inference Poster Early visual processing—data, theory, models Wichmann, F. Experimentelle Psychologie. Beitr{\"a}ge zur 46. Tagung experimentell arbeitender Psychologen, 46:24, 2004 BibTeX

Empirical Inference Conference Paper Efficient Approximations for Support Vector Machines in Object Detection Kienzle, W., BakIr, G., Franz, M., Schölkopf, B. In Pattern Recognition, Proceedings of the 26th DAGM Symposium, DAGM 2004, 54-61, (Editors: CE Rasmussen and HH Bülthoff and B Schölkopf and MA Giese), Springer, Berlin, Germany, Pattern Recognition, Proceedings of the 26th DAGM Symposium, 2004
We present a new approximation scheme for support vector decision functions in object detection. In the present approach we are building on an existing algorithm where the set of support vectors is replaced by a smaller so-called reduced set of synthetic points. Instead of finding the reduced set via unconstrained optimization, we impose a structural constraint on the synthetic vectors such that the resulting approximation can be evaluated via separable filters. Applications that require scanning an entire image can benefit from this representation: when using separable filters, the average computational complexity for evaluating a reduced set vector on a test patch of size (h x w) drops from O(hw) to O(h+w). We show experimental results on handwritten digits and face detection.
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Empirical Inference Article Feature Selection for Support Vector Machines Using Genetic Algorithms Fröhlich, H., Chapelle, O., Schölkopf, B. International Journal on Artificial Intelligence Tools (Special Issue on Selected Papers from the 15th IEEE International Conference on Tools with Artificial Intelligence 2003), 13(4):791-800, 2004 Web BibTeX

Empirical Inference Conference Paper Gasussian process model based predictive control Kocijan, J., Murray-Smith, R., Rasmussen, C., Girard, A. In Proceedings of the ACC 2004, 2214-2219, Proceedings of the ACC, 2004
Gaussian process models provide a probabilistic non-parametric modelling approach for black-box identi cation of non-linear dynamic systems. The Gaussian processes can highlight areas of the input space where prediction quality is poor, due to the lack of data or its complexity, by indicating the higher variance around the predicted mean. Gaussian process models contain noticeably less coef cients to be optimised. This paper illustrates possible application of Gaussian process models within model-based predictive control. The extra information provided within Gaussian process model is used in predictive control, where optimisation of control signal takes the variance information into account. The predictive control principle is demonstrated on control of pH process benchmark.
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Empirical Inference Book Chapter Gaussian Processes in Machine Learning Rasmussen, C. In 3176:63-71, Lecture Notes in Computer Science, (Editors: Bousquet, O., U. von Luxburg and G. Rätsch), Springer, Heidelberg, 2004, Copyright by Springer
We give a basic introduction to Gaussian Process regression models. We focus on understanding the role of the stochastic process and how it is used to define a distribution over functions. We present the simple equations for incorporating training data and examine how to learn the hyperparameters using the marginal likelihood. We explain the practical advantages of Gaussian Process and end with conclusions and a look at the current trends in GP work.
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Empirical Inference Conference Paper Hilbertian Metrics on Probability Measures and their Application in SVM’s Hein, H., Lal, T., Bousquet, O. In Pattern Recognition, Proceedings of th 26th DAGM Symposium, 3175:270-277, Lecture Notes in Computer Science, (Editors: Rasmussen, C. E., H. H. Bülthoff, M. Giese and B. Schölkopf), Pattern Recognition, Proceedings of th 26th DAGM Symposium, 2004
The goal of this article is to investigate the field of Hilbertian metrics on probability measures. Since they are very versatile and can therefore be applied in various problems they are of great interest in kernel methods. Quit recently Tops{o}e and Fuglede introduced a family of Hilbertian metrics on probability measures. We give basic properties of the Hilbertian metrics of this family and other used metrics in the literature. Then we propose an extension of the considered metrics which incorporates structural information of the probability space into the Hilbertian metric. Finally we compare all proposed metrics in an image and text classification problem using histogram data.
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Empirical Inference Poster Implicit Wiener series for capturing higher-order interactions in images Franz, M., Schölkopf, B. Sensory coding and the natural environment, (Editors: Olshausen, B.A. and M. Lewicki), 2004
The information about the objects in an image is almost exclusively described by the higher-order interactions of its pixels. The Wiener series is one of the standard methods to systematically characterize these interactions. However, the classical estimation method of the Wiener expansion coefficients via cross-correlation suffers from severe problems that prevent its application to high-dimensional and strongly nonlinear signals such as images. We propose an estimation method based on regression in a reproducing kernel Hilbert space that overcomes these problems using polynomial kernels as known from Support Vector Machines and other kernel-based methods. Numerical experiments show performance advantages in terms of convergence, interpretability and system sizes that can be handled. By the time of the conference, we will be able to present first results on the higher-order structure of natural images.
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