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2010


Decoding complete reach and grasp actions from local primary motor cortex populations
Decoding complete reach and grasp actions from local primary motor cortex populations

(Featured in Nature’s Research Highlights (Nature, Vol 466, 29 July 2010))

Vargas-Irwin, C. E., Shakhnarovich, G., Yadollahpour, P., Mislow, J., Black, M. J., Donoghue, J. P.

J. of Neuroscience, 39(29):9659-9669, July 2010 (article)

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pdf pdf from publisher Movie 1 Movie 2 Project Page [BibTex]

2010


pdf pdf from publisher Movie 1 Movie 2 Project Page [BibTex]


Guest editorial: State of the art in image- and video-based human pose and motion estimation
Guest editorial: State of the art in image- and video-based human pose and motion estimation

Sigal, L., Black, M. J.

International Journal of Computer Vision, 87(1):1-3, March 2010 (article)

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pdf from publisher [BibTex]

pdf from publisher [BibTex]


{HumanEva}: Synchronized video and motion capture dataset and baseline algorithm for evaluation of articulated human motion
HumanEva: Synchronized video and motion capture dataset and baseline algorithm for evaluation of articulated human motion

Sigal, L., Balan, A., Black, M. J.

International Journal of Computer Vision, 87(1):4-27, Springer Netherlands, March 2010 (article)

Abstract
While research on articulated human motion and pose estimation has progressed rapidly in the last few years, there has been no systematic quantitative evaluation of competing methods to establish the current state of the art. We present data obtained using a hardware system that is able to capture synchronized video and ground-truth 3D motion. The resulting HumanEva datasets contain multiple subjects performing a set of predefined actions with a number of repetitions. On the order of 40,000 frames of synchronized motion capture and multi-view video (resulting in over one quarter million image frames in total) were collected at 60 Hz with an additional 37,000 time instants of pure motion capture data. A standard set of error measures is defined for evaluating both 2D and 3D pose estimation and tracking algorithms. We also describe a baseline algorithm for 3D articulated tracking that uses a relatively standard Bayesian framework with optimization in the form of Sequential Importance Resampling and Annealed Particle Filtering. In the context of this baseline algorithm we explore a variety of likelihood functions, prior models of human motion and the effects of algorithm parameters. Our experiments suggest that image observation models and motion priors play important roles in performance, and that in a multi-view laboratory environment, where initialization is available, Bayesian filtering tends to perform well. The datasets and the software are made available to the research community. This infrastructure will support the development of new articulated motion and pose estimation algorithms, will provide a baseline for the evaluation and comparison of new methods, and will help establish the current state of the art in human pose estimation and tracking.

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pdf pdf from publisher [BibTex]

pdf pdf from publisher [BibTex]


 Automated Home-Cage Behavioral Phenotyping of Mice
Automated Home-Cage Behavioral Phenotyping of Mice

Jhuang, H., Garrote, E., Mutch, J., Poggio, T., Steele, A., Serre, T.

Nature Communications, Nature Communications, 2010 (article)

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software, demo pdf [BibTex]

software, demo pdf [BibTex]


Visual Object-Action Recognition: Inferring Object Affordances from Human Demonstration
Visual Object-Action Recognition: Inferring Object Affordances from Human Demonstration

Kjellström, H., Romero, J., Kragic, D.

Computer Vision and Image Understanding, pages: 81-90, 2010 (article)

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Pdf [BibTex]

Pdf [BibTex]

2009


Fields of Experts
Fields of Experts

Roth, S., Black, M. J.

International Journal of Computer Vision (IJCV), 82(2):205-29, April 2009 (article)

Abstract
We develop a framework for learning generic, expressive image priors that capture the statistics of natural scenes and can be used for a variety of machine vision tasks. The approach provides a practical method for learning high-order Markov random field (MRF) models with potential functions that extend over large pixel neighborhoods. These clique potentials are modeled using the Product-of-Experts framework that uses non-linear functions of many linear filter responses. In contrast to previous MRF approaches all parameters, including the linear filters themselves, are learned from training data. We demonstrate the capabilities of this Field-of-Experts model with two example applications, image denoising and image inpainting, which are implemented using a simple, approximate inference scheme. While the model is trained on a generic image database and is not tuned toward a specific application, we obtain results that compete with specialized techniques.

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pdf pdf from publisher [BibTex]

2009


pdf pdf from publisher [BibTex]


Left Ventricular Regional Wall Curvedness and Wall Stress in Patients with Ischemic Dilated Cardiomyopathy
Left Ventricular Regional Wall Curvedness and Wall Stress in Patients with Ischemic Dilated Cardiomyopathy

Liang Zhong, Yi Su, Si Yong Yeo, Ru San Tan Dhanjoo Ghista, Ghassan Kassab

American Journal of Physiology – Heart and Circulatory Physiology, 296(3):H573-84, 2009 (article)

Abstract
Geometric remodeling of the left ventricle (LV) after myocardial infarction is associated with changes in myocardial wall stress. The objective of this study was to determine the regional curvatures and wall stress based on three-dimensional (3-D) reconstructions of the LV using MRI. Ten patients with ischemic dilated cardiomyopathy (IDCM) and 10 normal subjects underwent MRI scan. The IDCM patients also underwent delayed gadolinium-enhancement imaging to delineate the extent of myocardial infarct. Regional curvedness, local radii of curvature, and wall thickness were calculated. The percent curvedness change between end diastole and end systole was also calculated. In normal heart, a short- and long-axis two-dimensional analysis showed a 41 +/- 11% and 45 +/- 12% increase of the mean of peak systolic wall stress between basal and apical sections, respectively. However, 3-D analysis showed no significant difference in peak systolic wall stress from basal and apical sections (P = 0.298, ANOVA). LV shape differed between IDCM patients and normal subjects in several ways: LV shape was more spherical (sphericity index = 0.62 +/- 0.08 vs. 0.52 +/- 0.06, P < 0.05), curvedness at end diastole (mean for 16 segments = 0.034 +/- 0.0056 vs. 0.040 +/- 0.0071 mm(-1), P < 0.001) and end systole (mean for 16 segments = 0.037 +/- 0.0068 vs. 0.067 +/- 0.020 mm(-1), P < 0.001) was affected by infarction, and peak systolic wall stress was significantly increased at each segment in IDCM patients. The 3-D quantification of regional wall stress by cardiac MRI provides more precise evaluation of cardiac mechanics. Identification of regional curvedness and wall stresses helps delineate the mechanisms of LV remodeling in IDCM and may help guide therapeutic LV restoration.

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[BibTex]

[BibTex]


A Curvature-Based Approach for Left Ventricular Shape Analysis from Cardiac Magnetic Resonance Imaging
A Curvature-Based Approach for Left Ventricular Shape Analysis from Cardiac Magnetic Resonance Imaging

Si Yong Yeo, Liang Zhong, Yi Su, Ru San Tan, Dhanjoo Ghista

Medical & Biological Engineering & Computing, 47(3):313-322, 2009 (article)

Abstract
It is believed that left ventricular (LV) regional shape is indicative of LV regional function, and cardiac pathologies are often associated with regional alterations in ventricular shape. In this article, we present a set of procedures for evaluating regional LV surface shape from anatomically accurate models reconstructed from cardiac magnetic resonance (MR) images. LV surface curvatures are computed using local surface fitting method, which enables us to assess regional LV shape and its variation. Comparisons are made between normal and diseased hearts. It is illustrated that LV surface curvatures at different regions of the normal heart are higher than those of the diseased heart. Also, the normal heart experiences a larger change in regional curvedness during contraction than the diseased heart. It is believed that with a wide range of dataset being evaluated, this approach will provide a new and efficient way of quantifying LV regional function.

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link (url) [BibTex]

link (url) [BibTex]

2008


A non-parametric {Bayesian} alternative to spike sorting
A non-parametric Bayesian alternative to spike sorting

Wood, F., Black, M. J.

J. Neuroscience Methods, 173(1):1–12, August 2008 (article)

Abstract
The analysis of extra-cellular neural recordings typically begins with careful spike sorting and all analysis of the data then rests on the correctness of the resulting spike trains. In many situations this is unproblematic as experimental and spike sorting procedures often focus on well isolated units. There is evidence in the literature, however, that errors in spike sorting can occur even with carefully collected and selected data. Additionally, chronically implanted electrodes and arrays with fixed electrodes cannot be easily adjusted to provide well isolated units. In these situations, multiple units may be recorded and the assignment of waveforms to units may be ambiguous. At the same time, analysis of such data may be both scientifically important and clinically relevant. In this paper we address this issue using a novel probabilistic model that accounts for several important sources of uncertainty and error in spike sorting. In lieu of sorting neural data to produce a single best spike train, we estimate a probabilistic model of spike trains given the observed data. We show how such a distribution over spike sortings can support standard neuroscientific questions while providing a representation of uncertainty in the analysis. As a representative illustration of the approach, we analyzed primary motor cortical tuning with respect to hand movement in data recorded with a chronic multi-electrode array in non-human primates.We found that the probabilistic analysis generally agrees with human sorters but suggests the presence of tuned units not detected by humans.

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pdf preprint pdf from publisher PubMed [BibTex]

2008


pdf preprint pdf from publisher PubMed [BibTex]


Neural control of computer cursor velocity by decoding motor cortical spiking activity in humans with tetraplegia
Neural control of computer cursor velocity by decoding motor cortical spiking activity in humans with tetraplegia

(J. Neural Engineering Highlights of 2008 Collection)

Kim, S., Simeral, J., Hochberg, L., Donoghue, J. P., Black, M. J.

J. Neural Engineering, 5, pages: 455–476, 2008 (article)

Abstract
Computer-mediated connections between human motor cortical neurons and assistive devices promise to improve or restore lost function in people with paralysis. Recently, a pilot clinical study of an intracortical neural interface system demonstrated that a tetraplegic human was able to obtain continuous two-dimensional control of a computer cursor using neural activity recorded from his motor cortex. This control, however, was not sufficiently accurate for reliable use in many common computer control tasks. Here, we studied several central design choices for such a system including the kinematic representation for cursor movement, the decoding method that translates neuronal ensemble spiking activity into a control signal and the cursor control task used during training for optimizing the parameters of the decoding method. In two tetraplegic participants, we found that controlling a cursor’s velocity resulted in more accurate closed-loop control than controlling its position directly and that cursor velocity control was achieved more rapidly than position control. Control quality was further improved over conventional linear filters by using a probabilistic method, the Kalman filter, to decode human motor cortical activity. Performance assessment based on standard metrics used for the evaluation of a wide range of pointing devices demonstrated significantly improved cursor control with velocity rather than position decoding.

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pdf preprint pdf from publisher [BibTex]

pdf preprint pdf from publisher [BibTex]


Brownian Warps for Non-Rigid Registration
Brownian Warps for Non-Rigid Registration

Mads Nielsen, Peter Johansen, Andrew Jackson, Benny Lautrup, Soren Hauberg

Journal of Mathematical Imaging and Vision, 31, pages: 221-231, Springer Netherlands, 2008 (article)

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Publishers site PDF [BibTex]

Publishers site PDF [BibTex]


 An Efficient Algorithm for Modelling Duration in Hidden Markov Models, with a Dramatic Application
An Efficient Algorithm for Modelling Duration in Hidden Markov Models, with a Dramatic Application

Soren Hauberg, Jakob Sloth

Journal of Mathematical Imaging and Vision, 31, pages: 165-170, Springer Netherlands, 2008 (article)

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Publishers site Paper site PDF [BibTex]

Publishers site Paper site PDF [BibTex]

2004


On the variability of manual spike sorting
On the variability of manual spike sorting

Wood, F., Black, M. J., Vargas-Irwin, C., Fellows, M., Donoghue, J. P.

IEEE Trans. Biomedical Engineering, 51(6):912-918, June 2004 (article)

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pdf pdf from publisher [BibTex]

2004


pdf pdf from publisher [BibTex]


Modeling and decoding motor cortical activity using a switching {Kalman} filter
Modeling and decoding motor cortical activity using a switching Kalman filter

Wu, W., Black, M. J., Mumford, D., Gao, Y., Bienenstock, E., Donoghue, J. P.

IEEE Trans. Biomedical Engineering, 51(6):933-942, June 2004 (article)

Abstract
We present a switching Kalman filter model for the real-time inference of hand kinematics from a population of motor cortical neurons. Firing rates are modeled as a Gaussian mixture where the mean of each Gaussian component is a linear function of hand kinematics. A “hidden state” models the probability of each mixture component and evolves over time in a Markov chain. The model generalizes previous encoding and decoding methods, addresses the non-Gaussian nature of firing rates, and can cope with crudely sorted neural data common in on-line prosthetic applications.

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pdf pdf from publisher [BibTex]

pdf pdf from publisher [BibTex]

1999


Parameterized modeling and recognition of activities
Parameterized modeling and recognition of activities

Yacoob, Y., Black, M. J.

Computer Vision and Image Understanding, 73(2):232-247, 1999 (article)

Abstract
In this paper we consider a class of human activities—atomic activities—which can be represented as a set of measurements over a finite temporal window (e.g., the motion of human body parts during a walking cycle) and which has a relatively small space of variations in performance. A new approach for modeling and recognition of atomic activities that employs principal component analysis and analytical global transformations is proposed. The modeling of sets of exemplar instances of activities that are similar in duration and involve similar body part motions is achieved by parameterizing their representation using principal component analysis. The recognition of variants of modeled activities is achieved by searching the space of admissible parameterized transformations that these activities can undergo. This formulation iteratively refines the recognition of the class to which the observed activity belongs and the transformation parameters that relate it to the model in its class. We provide several experiments on recognition of articulated and deformable human motions from image motion parameters.

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pdf pdf from publisher DOI [BibTex]

1999


pdf pdf from publisher DOI [BibTex]

1994


A computational and evolutionary perspective on the role of representation in computer vision
A computational and evolutionary perspective on the role of representation in computer vision

Tarr, M. J., Black, M. J.

CVGIP: Image Understanding, 60(1):65-73, July 1994 (article)

Abstract
Recently, the assumed goal of computer vision, reconstructing a representation of the scene, has been critcized as unproductive and impractical. Critics have suggested that the reconstructive approach should be supplanted by a new purposive approach that emphasizes functionality and task driven perception at the cost of general vision. In response to these arguments, we claim that the recovery paradigm central to the reconstructive approach is viable, and, moreover, provides a promising framework for understanding and modeling general purpose vision in humans and machines. An examination of the goals of vision from an evolutionary perspective and a case study involving the recovery of optic flow support this hypothesis. In particular, while we acknowledge that there are instances where the purposive approach may be appropriate, these are insufficient for implementing the wide range of visual tasks exhibited by humans (the kind of flexible vision system presumed to be an end-goal of artificial intelligence). Furthermore, there are instances, such as recent work on the estimation of optic flow, where the recovery paradigm may yield useful and robust results. Thus, contrary to certain claims, the purposive approach does not obviate the need for recovery and reconstruction of flexible representations of the world.

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pdf [BibTex]

1994


pdf [BibTex]


Reconstruction and purpose
Reconstruction and purpose

Tarr, M. J., Black, M. J.

CVGIP: Image Understanding, 60(1):113-118, July 1994 (article)

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pdf [BibTex]

pdf [BibTex]