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2019


Thumb xl screenshot 2019 04 08 at 16.22.00
Effect of Remote Masking on Detection of Electrovibration

Jamalzadeh, M., Güçlü, B., Vardar, Y., Basdogan, C.

In Proceedings of the IEEE World Haptics Conference (WHC), pages: 229-234, Tokyo, Japan, July 2019 (inproceedings)

Abstract
Masking has been used to study human perception of tactile stimuli, including those created on haptic touch screens. Earlier studies have investigated the effect of in-site masking on tactile perception of electrovibration. In this study, we investigated whether it is possible to change detection threshold of electrovibration at fingertip of index finger via remote masking, i.e. by applying a (mechanical) vibrotactile stimulus on the proximal phalanx of the same finger. The masking stimuli were generated by a voice coil (Haptuator). For eight participants, we first measured the detection thresholds for electrovibration at the fingertip and for vibrotactile stimuli at the proximal phalanx. Then, the vibrations on the skin were measured at four different locations on the index finger of subjects to investigate how the mechanical masking stimulus propagated as the masking level was varied. Finally, electrovibration thresholds measured in the presence of vibrotactile masking stimuli. Our results show that vibrotactile masking stimuli generated sub-threshold vibrations around fingertip, and hence did not mechanically interfere with the electrovibration stimulus. However, there was a clear psychophysical masking effect due to central neural processes. Electrovibration absolute threshold increased approximately 0.19 dB for each dB increase in the masking level.

hi

DOI [BibTex]

2019


DOI [BibTex]


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Objective and Subjective Assessment of Algorithms for Reducing Three-Axis Vibrations to One-Axis Vibrations

Park, G., Kuchenbecker, K. J.

In Proceedings of the IEEE World Haptics Conference, pages: 467-472, July 2019 (inproceedings)

Abstract
A typical approach to creating realistic vibrotactile feedback is reducing 3D vibrations recorded by an accelerometer to 1D signals that can be played back on a haptic actuator, but some of the information is often lost in this dimensional reduction process. This paper describes seven representative algorithms and proposes four metrics based on the spectral match, the temporal match, and the average value and the variability of them across 3D rotations. These four performance metrics were applied to four texture recordings, and the method utilizing the discrete fourier transform (DFT) was found to be the best regardless of the sensing axis. We also recruited 16 participants to assess the perceptual similarity achieved by each algorithm in real time. We found the four metrics correlated well with the subjectively rated similarities for the six dimensional reduction algorithms, with the exception of taking the 3D vector magnitude, which was perceived to be good despite its low spectral and temporal match metrics.

hi

DOI [BibTex]

DOI [BibTex]


Thumb xl screenshot 2019 04 08 at 16.08.19
Fingertip Interaction Metrics Correlate with Visual and Haptic Perception of Real Surfaces

Vardar, Y., Wallraven, C., Kuchenbecker, K. J.

In Proceedings of the IEEE World Haptics Conference (WHC), pages: 395-400, Tokyo, Japan, July 2019 (inproceedings)

Abstract
Both vision and touch contribute to the perception of real surfaces. Although there have been many studies on the individual contributions of each sense, it is still unclear how each modality’s information is processed and integrated. To fill this gap, we investigated the similarity of visual and haptic perceptual spaces, as well as how well they each correlate with fingertip interaction metrics. Twenty participants interacted with ten different surfaces from the Penn Haptic Texture Toolkit by either looking at or touching them and judged their similarity in pairs. By analyzing the resulting similarity ratings using multi-dimensional scaling (MDS), we found that surfaces are similarly organized within the three-dimensional perceptual spaces of both modalities. Also, between-participant correlations were significantly higher in the haptic condition. In a separate experiment, we obtained the contact forces and accelerations acting on one finger interacting with each surface in a controlled way. We analyzed the collected fingertip interaction data in both the time and frequency domains. Our results suggest that the three perceptual dimensions for each modality can be represented by roughness/smoothness, hardness/softness, and friction, and that these dimensions can be estimated by surface vibration power, tap spectral centroid, and kinetic friction coefficient, respectively.

hi

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Internal Array Electrodes Improve the Spatial Resolution of Soft Tactile Sensors Based on Electrical Resistance Tomography

Lee, H., Park, K., Kim, J., Kuchenbecker, K. J.

In Proceedings of the IEEE International Conference on Robotics and Automation (ICRA), pages: 5411-5417, Montreal, Canada, May 2019, Hyosang Lee and Kyungseo Park contributed equally to this publication (inproceedings)

hi

link (url) DOI Project Page [BibTex]

link (url) DOI Project Page [BibTex]


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Haptipedia: Accelerating Haptic Device Discovery to Support Interaction & Engineering Design

Seifi, H., Fazlollahi, F., Oppermann, M., Sastrillo, J. A., Ip, J., Agrawal, A., Park, G., Kuchenbecker, K. J., MacLean, K. E.

In Proceedings of the ACM SIGCHI Conference on Human Factors in Computing Systems (CHI), Glasgow, Scotland, May 2019 (inproceedings)

Abstract
Creating haptic experiences often entails inventing, modifying, or selecting specialized hardware. However, experience designers are rarely engineers, and 30 years of haptic inventions are buried in a fragmented literature that describes devices mechanically rather than by potential purpose. We conceived of Haptipedia to unlock this trove of examples: Haptipedia presents a device corpus for exploration through metadata that matter to both device and experience designers. It is a taxonomy of device attributes that go beyond physical description to capture potential utility, applied to a growing database of 105 grounded force-feedback devices, and accessed through a public visualization that links utility to morphology. Haptipedia's design was driven by both systematic review of the haptic device literature and rich input from diverse haptic designers. We describe Haptipedia's reception (including hopes it will redefine device reporting standards) and our plans for its sustainability through community participation.

hi

Project Page [BibTex]

Project Page [BibTex]


Thumb xl robot
Improving Haptic Adjective Recognition with Unsupervised Feature Learning

Richardson, B. A., Kuchenbecker, K. J.

In Proceedings of the IEEE International Conference on Robotics and Automation (ICRA), pages: 3804-3810, Montreal, Canada, May 2019 (inproceedings)

Abstract
Humans can form an impression of how a new object feels simply by touching its surfaces with the densely innervated skin of the fingertips. Many haptics researchers have recently been working to endow robots with similar levels of haptic intelligence, but these efforts almost always employ hand-crafted features, which are brittle, and concrete tasks, such as object recognition. We applied unsupervised feature learning methods, specifically K-SVD and Spatio-Temporal Hierarchical Matching Pursuit (ST-HMP), to rich multi-modal haptic data from a diverse dataset. We then tested the learned features on 19 more abstract binary classification tasks that center on haptic adjectives such as smooth and squishy. The learned features proved superior to traditional hand-crafted features by a large margin, almost doubling the average F1 score across all adjectives. Additionally, particular exploratory procedures (EPs) and sensor channels were found to support perception of certain haptic adjectives, underlining the need for diverse interactions and multi-modal haptic data.

hi

link (url) DOI Project Page [BibTex]

link (url) DOI Project Page [BibTex]


Thumb xl screenshot 2019 02 03 at 19.15.13
A Novel Texture Rendering Approach for Electrostatic Displays

Fiedler, T., Vardar, Y.

In Proceedings of International Workshop on Haptic and Audio Interaction Design (HAID), Lille, France, March 2019 (inproceedings)

Abstract
Generating realistic texture feelings on tactile displays using data-driven methods has attracted a lot of interest in the last decade. However, the need for large data storages and transmission rates complicates the use of these methods for the future commercial displays. In this paper, we propose a new texture rendering approach which can compress the texture data signicantly for electrostatic displays. Using three sample surfaces, we first explain how to record, analyze and compress the texture data, and render them on a touchscreen. Then, through psychophysical experiments conducted with nineteen participants, we show that the textures can be reproduced by a signicantly less number of frequency components than the ones in the original signal without inducing perceptual degradation. Moreover, our results indicate that the possible degree of compression is affected by the surface properties.

hi

Fiedler19-HAID-Electrostatic [BibTex]

Fiedler19-HAID-Electrostatic [BibTex]

2018


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Gait learning for soft microrobots controlled by light fields

Rohr, A. V., Trimpe, S., Marco, A., Fischer, P., Palagi, S.

In International Conference on Intelligent Robots and Systems (IROS) 2018, pages: 6199-6206, International Conference on Intelligent Robots and Systems 2018, October 2018 (inproceedings)

Abstract
Soft microrobots based on photoresponsive materials and controlled by light fields can generate a variety of different gaits. This inherent flexibility can be exploited to maximize their locomotion performance in a given environment and used to adapt them to changing environments. However, because of the lack of accurate locomotion models, and given the intrinsic variability among microrobots, analytical control design is not possible. Common data-driven approaches, on the other hand, require running prohibitive numbers of experiments and lead to very sample-specific results. Here we propose a probabilistic learning approach for light-controlled soft microrobots based on Bayesian Optimization (BO) and Gaussian Processes (GPs). The proposed approach results in a learning scheme that is highly data-efficient, enabling gait optimization with a limited experimental budget, and robust against differences among microrobot samples. These features are obtained by designing the learning scheme through the comparison of different GP priors and BO settings on a semisynthetic data set. The developed learning scheme is validated in microrobot experiments, resulting in a 115% improvement in a microrobot’s locomotion performance with an experimental budget of only 20 tests. These encouraging results lead the way toward self-adaptive microrobotic systems based on lightcontrolled soft microrobots and probabilistic learning control.

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arXiv IEEE Xplore DOI Project Page [BibTex]

2018


arXiv IEEE Xplore DOI Project Page [BibTex]


Thumb xl icra2018
Soft Miniaturized Linear Actuators Wirelessly Powered by Rotating Permanent Magnets

Qiu, T., Palagi, S., Sachs, J., Fischer, P.

In 2018 IEEE International Conference on Robotics and Automation (ICRA), pages: 3595-3600, May 2018 (inproceedings)

Abstract
Wireless actuation by magnetic fields allows for the operation of untethered miniaturized devices, e.g. in biomedical applications. Nevertheless, generating large controlled forces over relatively large distances is challenging. Magnetic torques are easier to generate and control, but they are not always suitable for the tasks at hand. Moreover, strong magnetic fields are required to generate a sufficient torque, which are difficult to achieve with electromagnets. Here, we demonstrate a soft miniaturized actuator that transforms an externally applied magnetic torque into a controlled linear force. We report the design, fabrication and characterization of both the actuator and the magnetic field generator. We show that the magnet assembly, which is based on a set of rotating permanent magnets, can generate strong controlled oscillating fields over a relatively large workspace. The actuator, which is 3D-printed, can lift a load of more than 40 times its weight. Finally, we show that the actuator can be further miniaturized, paving the way towards strong, wirelessly powered microactuators.

pf

link (url) DOI [BibTex]

link (url) DOI [BibTex]

2017


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Synchronicity Trumps Mischief in Rhythmic Human-Robot Social-Physical Interaction

Fitter, N. T., Kuchenbecker, K. J.

In Proceedings of the International Symposium on Robotics Research (ISRR), Puerto Varas, Chile, December 2017 (inproceedings) In press

Abstract
Hand-clapping games and other forms of rhythmic social-physical interaction might help foster human-robot teamwork, but the design of such interactions has scarcely been explored. We leveraged our prior work to enable the Rethink Robotics Baxter Research Robot to competently play one-handed tempo-matching hand-clapping games with a human user. To understand how such a robot’s capabilities and behaviors affect user perception, we created four versions of this interaction: the hand clapping could be initiated by either the robot or the human, and the non-initiating partner could be either cooperative, yielding synchronous motion, or mischievously uncooperative. Twenty adults tested two clapping tempos in each of these four interaction modes in a random order, rating every trial on standardized scales. The study results showed that having the robot initiate the interaction gave it a more dominant perceived personality. Despite previous results on the intrigue of misbehaving robots, we found that moving synchronously with the robot almost always made the interaction more enjoyable, less mentally taxing, less physically demanding, and lower effort for users than asynchronous interactions caused by robot or human mischief. Taken together, our results indicate that cooperative rhythmic social-physical interaction has the potential to strengthen human-robot partnerships.

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[BibTex]

2017


[BibTex]


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Stiffness Perception during Pinching and Dissection with Teleoperated Haptic Forceps

Ng, C., Zareinia, K., Sun, Q., Kuchenbecker, K. J.

In Proceedings of the International Symposium on Robot and Human Interactive Communication (RO-MAN), pages: 456-463, Lisbon, Portugal, August 2017 (inproceedings)

hi

link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Locomotion of light-driven soft microrobots through a hydrogel via local melting

Palagi, S., Mark, A. G., Melde, K., Qiu, T., Zeng, H., Parmeggiani, C., Martella, D., Wiersma, D. S., Fischer, P.

In 2017 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), pages: 1-5, July 2017 (inproceedings)

Abstract
Soft mobile microrobots whose deformation can be directly controlled by an external field can adapt to move in different environments. This is the case for the light-driven microrobots based on liquid-crystal elastomers (LCEs). Here we show that the soft microrobots can move through an agarose hydrogel by means of light-controlled travelling-wave motions. This is achieved by exploiting the inherent rise of the LCE temperature above the melting temperature of the agarose gel, which facilitates penetration of the microrobot through the hydrogel. The locomotion performance is investigated as a function of the travelling-wave parameters, showing that effective propulsion can be obtained by adapting the generated motion to the specific environmental conditions.

pf

DOI [BibTex]

DOI [BibTex]


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Design of a Parallel Continuum Manipulator for 6-DOF Fingertip Haptic Display

Young, E. M., Kuchenbecker, K. J.

In Proceedings of the IEEE World Haptics Conference (WHC), pages: 599-604, Munich, Germany, June 2017, Finalist for best poster paper (inproceedings)

Abstract
Despite rapid advancements in the field of fingertip haptics, rendering tactile cues with six degrees of freedom (6 DOF) remains an elusive challenge. In this paper, we investigate the potential of displaying fingertip haptic sensations with a 6-DOF parallel continuum manipulator (PCM) that mounts to the user's index finger and moves a contact platform around the fingertip. Compared to traditional mechanisms composed of rigid links and discrete joints, PCMs have the potential to be strong, dexterous, and compact, but they are also more complicated to design. We define the design space of 6-DOF parallel continuum manipulators and outline a process for refining such a device for fingertip haptic applications. Following extensive simulation, we obtain 12 designs that meet our specifications, construct a manually actuated prototype of one such design, and evaluate the simulation's ability to accurately predict the prototype's motion. Finally, we demonstrate the range of deliverable fingertip tactile cues, including a normal force into the finger and shear forces tangent to the finger at three extreme points on the boundary of the fingertip.

hi

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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High Magnitude Unidirectional Haptic Force Display Using a Motor/Brake Pair and a Cable

Hu, S., Kuchenbecker, K. J.

In Proceedings of the IEEE World Haptics Conference (WHC), pages: 394-399, Munich, Germany, June 2017 (inproceedings)

Abstract
Clever electromechanical design is required to make the force feedback delivered by a kinesthetic haptic interface both strong and safe. This paper explores a onedimensional haptic force display that combines a DC motor and a magnetic particle brake on the same shaft. Rather than a rigid linkage, a spooled cable connects the user to the actuators to enable a large workspace, reduce the moving mass, and eliminate the sticky residual force from the brake. This design combines the high torque/power ratio of the brake and the active output capabilities of the motor to provide a wider range of forces than can be achieved with either actuator alone. A prototype of this device was built, its performance was characterized, and it was used to simulate constant force sources and virtual springs and dampers. Compared to the conventional design of using only a motor, the hybrid device can output higher unidirectional forces at the expense of free space feeling less free.

hi

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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A Wrist-Squeezing Force-Feedback System for Robotic Surgery Training

Brown, J. D., Fernandez, J. N., Cohen, S. P., Kuchenbecker, K. J.

In Proceedings of the IEEE World Haptics Conference (WHC), pages: 107-112, Munich, Germany, June 2017 (inproceedings)

Abstract
Over time, surgical trainees learn to compensate for the lack of haptic feedback in commercial robotic minimally invasive surgical systems. Incorporating touch cues into robotic surgery training could potentially shorten this learning process if the benefits of haptic feedback were sustained after it is removed. In this paper, we develop a wrist-squeezing haptic feedback system and evaluate whether it holds the potential to train novice da Vinci users to reduce the force they exert on a bimanual inanimate training task. Subjects were randomly divided into two groups according to a multiple baseline experimental design. Each of the ten participants moved a ring along a curved wire nine times while the haptic feedback was conditionally withheld, provided, and withheld again. The realtime tactile feedback of applied force magnitude significantly reduced the integral of the force produced by the da Vinci tools on the task materials, and this result remained even when the haptic feedback was removed. Overall, our findings suggest that wrist-squeezing force feedback can play an essential role in helping novice trainees learn to minimize the force they exert with a surgical robot.

hi

DOI [BibTex]

DOI [BibTex]


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Handling Scan-Time Parameters in Haptic Surface Classification

Burka, A., Kuchenbecker, K. J.

In Proceedings of the IEEE World Haptics Conference (WHC), pages: 424-429, Munich, Germany, June 2017 (inproceedings)

hi

DOI Project Page [BibTex]

DOI Project Page [BibTex]


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Proton 2: Increasing the Sensitivity and Portability of a Visuo-haptic Surface Interaction Recorder

Burka, A., Rajvanshi, A., Allen, S., Kuchenbecker, K. J.

In Proceedings of the IEEE International Conference on Robotics and Automation (ICRA), pages: 439-445, Singapore, May 2017 (inproceedings)

Abstract
The Portable Robotic Optical/Tactile ObservatioN PACKage (PROTONPACK, or Proton for short) is a new handheld visuo-haptic sensing system that records surface interactions. We previously demonstrated system calibration and a classification task using external motion tracking. This paper details improvements in surface classification performance and removal of the dependence on external motion tracking, necessary before embarking on our goal of gathering a vast surface interaction dataset. Two experiments were performed to refine data collection parameters. After adjusting the placement and filtering of the Proton's high-bandwidth accelerometers, we recorded interactions between two differently-sized steel tooling ball end-effectors (diameter 6.35 and 9.525 mm) and five surfaces. Using features based on normal force, tangential force, end-effector speed, and contact vibration, we trained multi-class SVMs to classify the surfaces using 50 ms chunks of data from each end-effector. Classification accuracies of 84.5% and 91.5% respectively were achieved on unseen test data, an improvement over prior results. In parallel, we pursued on-board motion tracking, using the Proton's camera and fiducial markers. Motion tracks from the external and onboard trackers agree within 2 mm and 0.01 rad RMS, and the accuracy decreases only slightly to 87.7% when using onboard tracking for the 9.525 mm end-effector. These experiments indicate that the Proton 2 is ready for portable data collection.

hi

DOI Project Page [BibTex]

DOI Project Page [BibTex]


Thumb xl eururol2017
Wireless micro-robots for endoscopic applications in urology

Adams, F., Qiu, T., Mark, A. G., Melde, K., Palagi, S., Miernik, A., Fischer, P.

In Eur Urol Suppl, 16(3):e1914, March 2017 (inproceedings)

Abstract
Endoscopy is an essential and common method for both diagnostics and therapy in Urology. Current flexible endoscope is normally cable-driven, thus it is hard to be miniaturized and its reachability is restricted as only one bending section near the tip with one degree of freedom (DoF) is allowed. Recent progresses in micro-robotics offer a unique opportunity for medical inspections in minimally invasive surgery. Micro-robots are active devices that has a feature size smaller than one millimeter and can normally be actuated and controlled wirelessly. Magnetically actuated micro-robots have been demonstrated to propel through biological fluids.Here, we report a novel micro robotic arm, which is actuated wirelessly by ultrasound. It works as a miniaturized endoscope with a side length of ~1 mm, which fits through the 3 Fr. tool channel of a cystoscope, and successfully performs an active cystoscopy in a rabbit bladder.

pf

link (url) DOI [BibTex]

2016


Thumb xl fig1
Soft continuous microrobots with multiple intrinsic degrees of freedom

Palagi, S., Mark, A. G., Melde, K., Zeng, H., Parmeggiani, C., Martella, D., Wiersma, D. S., Fischer, P.

In 2016 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), pages: 1-5, July 2016 (inproceedings)

Abstract
One of the main challenges in the development of microrobots, i.e. robots at the sub-millimeter scale, is the difficulty of adopting traditional solutions for power, control and, especially, actuation. As a result, most current microrobots are directly manipulated by external fields, and possess only a few passive degrees of freedom (DOFs). We have reported a strategy that enables embodiment, remote powering and control of a large number of DOFs in mobile soft microrobots. These consist of photo-responsive materials, such that the actuation of their soft continuous body can be selectively and dynamically controlled by structured light fields. Here we use finite-element modelling to evaluate the effective number of DOFs that are addressable in our microrobots. We also demonstrate that by this flexible approach different actuation patterns can be obtained, and thus different locomotion performances can be achieved within the very same microrobot. The reported results confirm the versatility of the proposed approach, which allows for easy application-specific optimization and online reconfiguration of the microrobot's behavior. Such versatility will enable advanced applications of robotics and automation at the micro scale.

pf

DOI [BibTex]

2016


DOI [BibTex]


Thumb xl marss2016
Wireless actuator based on ultrasonic bubble streaming

Qiu, T., Palagi, S., Mark, A. G., Melde, K., Fischer, P.

In 2016 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), pages: 1-5, July 2016 (inproceedings)

Abstract
Miniaturized actuators are a key element for the manipulation and automation at small scales. Here, we propose a new miniaturized actuator, which consists of an array of micro gas bubbles immersed in a fluid. Under ultrasonic excitation, the oscillation of micro gas bubbles results in acoustic streaming and provides a propulsive force that drives the actuator. The actuator was fabricated by lithography and fluidic streaming was observed under ultrasound excitation. Theoretical modelling and numerical simulations were carried out to show that lowing the surface tension results in a larger amplitude of the bubble oscillation, and thus leads to a higher propulsive force. Experimental results also demonstrate that the propulsive force increases 3.5 times when the surface tension is lowered by adding a surfactant. An actuator with a 4×4 mm 2 surface area provides a driving force of about 0.46 mN, suggesting that it is possible to be used as a wireless actuator for small-scale robots and medical instruments.

pf

link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Auxetic Metamaterial Simplifies Soft Robot Design

Mark, A. G., Palagi, S., Qiu, T., Fischer, P.

In 2016 IEEE Int. Conf. on Robotics and Automation (ICRA), pages: 4951-4956, May 2016 (inproceedings)

Abstract
Soft materials are being adopted in robotics in order to facilitate biomedical applications and in order to achieve simpler and more capable robots. One route to simplification is to design the robot's body using `smart materials' that carry the burden of control and actuation. Metamaterials enable just such rational design of the material properties. Here we present a soft robot that exploits mechanical metamaterials for the intrinsic synchronization of two passive clutches which contact its travel surface. Doing so allows it to move through an enclosed passage with an inchworm motion propelled by a single actuator. Our soft robot consists of two 3D-printed metamaterials that implement auxetic and normal elastic properties. The design, fabrication and characterization of the metamaterials are described. In addition, a working soft robot is presented. Since the synchronization mechanism is a feature of the robot's material body, we believe that the proposed design will enable compliant and robust implementations that scale well with miniaturization.

pf

link (url) DOI [BibTex]

link (url) DOI [BibTex]


Thumb xl spie2016
Towards Photo-Induced Swimming: Actuation of Liquid Crystalline Elastomer in Water

cerretti, G., Martella, D., Zeng, H., Parmeggiani, C., Palagi, S., Mark, A. G., Melde, K., Qiu, T., Fischer, P., Wiersma, D.

In Proc. of SPIE 9738, pages: Laser 3D Manufacturing III, 97380T, April 2016 (inproceedings)

Abstract
Liquid Crystalline Elastomers (LCEs) are very promising smart materials that can be made sensitive to different external stimuli, such as heat, pH, humidity and light, by changing their chemical composition. In this paper we report the implementation of a nematically aligned LCE actuator able to undergo large light-induced deformations. We prove that this property is still present even when the actuator is submerged in fresh water. Thanks to the presence of azo-dye moieties, capable of going through a reversible trans-cis photo-isomerization, and by applying light with two different wavelengths we managed to control the bending of such actuator in the liquid environment. The reported results represent the first step towards swimming microdevices powered by light.

pf

link (url) DOI [BibTex]

link (url) DOI [BibTex]

2015


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3D-printed Soft Microrobot for Swimming in Biological Fluids

Qiu, T., Palagi, S., Fischer, P.

In Conf. Proc. IEEE Eng. Med. Biol. Soc., pages: 4922-4925, August 2015 (inproceedings)

Abstract
Microscopic artificial swimmers hold the potential to enable novel non-invasive medical procedures. In order to ease their translation towards real biomedical applications, simpler designs as well as cheaper yet more reliable materials and fabrication processes should be adopted, provided that the functionality of the microrobots can be kept. A simple single-hinge design could already enable microswimming in non-Newtonian fluids, which most bodily fluids are. Here, we address the fabrication of such single-hinge microrobots with a 3D-printed soft material. Firstly, a finite element model is developed to investigate the deformability of the 3D-printed microstructure under typical values of the actuating magnetic fields. Then the microstructures are fabricated by direct 3D-printing of a soft material and their swimming performances are evaluated. The speeds achieved with the 3D-printed microrobots are comparable to those obtained in previous work with complex fabrication procedures, thus showing great promise for 3D-printed microrobots to be operated in biological fluids.

pf

link (url) DOI [BibTex]

2015


link (url) DOI [BibTex]

2014


Thumb xl fig1
3D nanofabrication on complex seed shapes using glancing angle deposition

Hyeon-Ho, J., Mark, A. G., Gibbs, J. G., Reindl, T., Waizmann, U., Weis, J., Fischer, P.

In 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS), pages: 437-440, January 2014 (inproceedings)

Abstract
Three-dimensional (3D) fabrication techniques promise new device architectures and enable the integration of more components, but fabricating 3D nanostructures for device applications remains challenging. Recently, we have performed glancing angle deposition (GLAD) upon a nanoscale hexagonal seed array to create a variety of 3D nanoscale objects including multicomponent rods, helices, and zigzags [1]. Here, in an effort to generalize our technique, we present a step-by-step approach to grow 3D nanostructures on more complex nanoseed shapes and configurations than before. This approach allows us to create 3D nanostructures on nanoseeds regardless of seed sizes and shapes.

pf

DOI [BibTex]

2014


DOI [BibTex]


Thumb xl toc image
Active Microrheology of the Vitreous of the Eye applied to Nanorobot Propulsion

Qiu, T., Schamel, D., Mark, A. G., Fischer, P.

In 2014 IEEE INTERNATIONAL CONFERENCE ON ROBOTICS AND AUTOMATION (ICRA), pages: 3801-3806, IEEE International Conference on Robotics and Automation ICRA, 2014, Best Automation Paper Award – Finalist. (inproceedings)

Abstract
Biomedical applications of micro or nanorobots require active movement through complex biological fluids. These are generally non-Newtonian (viscoelastic) fluids that are characterized by complicated networks of macromolecules that have size-dependent rheological properties. It has been suggested that an untethered microrobot could assist in retinal surgical procedures. To do this it must navigate the vitreous humor, a hydrated double network of collagen fibrils and high molecular-weight, polyanionic hyaluronan macromolecules. Here, we examine the characteristic size that potential robots must have to traverse vitreous relatively unhindered. We have constructed magnetic tweezers that provide a large gradient of up to 320 T/m to pull sub-micron paramagnetic beads through biological fluids. A novel two-step electrical discharge machining (EDM) approach is used to construct the tips of the magnetic tweezers with a resolution of 30 mu m and high aspect ratio of similar to 17:1 that restricts the magnetic field gradient to the plane of observation. We report measurements on porcine vitreous. In agreement with structural data and passive Brownian diffusion studies we find that the unhindered active propulsion through the eye calls for nanorobots with cross-sections of less than 500 nm.

Best Automation Paper Award – Finalist.

pf

[BibTex]

[BibTex]