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2019


Thumb xl fire
Controlling Heterogeneous Stochastic Growth Processes on Lattices with Limited Resources

Haksar, R., Solowjow, F., Trimpe, S., Schwager, M.

In Proceedings of the 58th IEEE International Conference on Decision and Control (CDC) , 58th IEEE International Conference on Decision and Control (CDC), December 2019 (proceedings) Accepted

ics

PDF [BibTex]

2019


PDF [BibTex]


Thumb xl 0050 samples slip fig
A Learnable Safety Measure

Heim, S., Rohr, A. V., Trimpe, S., Badri-Spröwitz, A.

Conference on Robot Learning, November 2019 (conference) Accepted

dlg ics

Arxiv [BibTex]

Arxiv [BibTex]


Thumb xl mode changes long exp
Fast Feedback Control over Multi-hop Wireless Networks with Mode Changes and Stability Guarantees

Baumann, D., Mager, F., Jacob, R., Thiele, L., Zimmerling, M., Trimpe, S.

ACM Transactions on Cyber-Physical Systems, 4(2), November 2019 (article) In press

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arXiv PDF DOI [BibTex]

arXiv PDF DOI [BibTex]


Thumb xl cell patterning with acoustic hologram
Acoustic Holographic Cell Patterning in a Biocompatible Hydrogel

Ma, Z., Holle, A., Melde, K., Qiu, T., Poeppel, K., Kadiri, V., Fischer, P.

Adv. Mat., October 2019 (article)

Abstract
Acoustophoresis is promising as a rapid, biocompatible, non-contact cell manipulation method, where cells are arranged along the nodes or antinodes of the acoustic field. Typically, the acoustic field is formed in a resonator, which results in highly symmetric regular patterns. However, arbitrary, non-symmetrically shaped cell assemblies are necessary to obtain the irregular cellular arrangements found in biological tissues. We show that arbitrarily shaped cell patterns can be obtained from the complex acoustic field distribution defined by an acoustic hologram. Attenuation of the sound field induces localized acoustic streaming and the resultant convection flow gently delivers the suspended cells to the image plane where they form the designed pattern. We show that the process can be implemented in a biocompatible collagen solution, which can then undergo gelation to immobilize the cell pattern inside the viscoelastic matrix. The patterned cells exhibit F-actin-based protrusions, which indicates that the cells grow and thrive within the matrix. Cell viability assays and brightfield imaging after one week confirm cell survival and that the patterns persist. Acoustophoretic cell manipulation by holographic fields thus holds promise for non-contact, long-range, long-term cellular pattern formation, with a wide variety of potential applications in tissue engineering and mechanobiology.

pf

[BibTex]


Thumb xl phantom surgery
A High-Fidelity Phantom for the Simulation and Quantitative Evaluation of Transurethral Resection of the Prostate

Choi, E., Adams, F., Gengenbacher, A., Schlager, D., Palagi, S., Müller, P., Wetterauer, U., Miernik, A., Fischer, P., Qiu, T.

Annals of Biomed. Eng., October 2019 (article)

Abstract
Transurethral resection of the prostate (TURP) is a minimally invasive endoscopic procedure that requires experience and skill of the surgeon. To permit surgical training under realistic conditions we report a novel phantom of the human prostate that can be resected with TURP. The phantom mirrors the anatomy and haptic properties of the gland and permits quantitative evaluation of important surgical performance indicators. Mixtures of soft materials are engineered to mimic the physical properties of the human tissue, including the mechanical strength, the electrical and thermal conductivity, and the appearance under an endoscope. Electrocautery resection of the phantom closely resembles the procedure on human tissue. Ultrasound contrast agent was applied to the central zone, which was not detectable by the surgeon during the surgery but showed high contrast when imaged after the surgery, to serve as a label for the quantitative evaluation of the surgery. Quantitative criteria for performance assessment are established and evaluated by automated image analysis. We present the workflow of a surgical simulation on a prostate phantom followed by quantitative evaluation of the surgical performance. Surgery on the phantom is useful for medical training, and enables the development and testing of endoscopic and minimally invasive surgical instruments.

pf

link (url) DOI [BibTex]

link (url) DOI [BibTex]


Thumb xl vision
Interactive Materials – Drivers of Future Robotic Systems

Fischer, P.

Adv. Mat., October 2019 (article)

Abstract
A robot senses its environment, processes the sensory information, acts in response to these inputs, and possibly communicates with the outside world. Robots generally achieve these tasks with electronics-based hardware or by receiving inputs from some external hardware. In contrast, simple microorganisms can autonomously perceive, act, and communicate via purely physicochemical processes in soft material systems. A key property of biological systems is that they are built from energy-consuming ‘active’ units. Exciting developments in material science show that even very simple artificial active building blocks can show surprisingly rich emergent behaviors. Active non-equilibrium systems are therefore predicted to play an essential role to realize interactive materials. A major challenge is to find robust ways to couple and integrate the energy-consuming building blocks to the mechanical structure of the material. However, success in this endeavor will lead to a new generation of sophisticated micro- and soft-robotic systems that can operate autonomously.

pf

[BibTex]


Thumb xl plasmonic dimers
Arrays of plasmonic nanoparticle dimers with defined nanogap spacers

Jeong, H., Adams, M. C., Guenther, J., Alarcon-Correa, M., Kim, I., Choi, E., Miksch, C., Mark, A. F. M., Mark, A. G., Fischer, P.

ACS Nano, September 2019 (article)

Abstract
Plasmonic molecules are building blocks of metallic nanostructures that give rise to intriguing optical phenomena with similarities to those seen in molecular systems. The ability to design plasmonic hybrid structures and molecules with nanometric resolution would enable applications in optical metamaterials and sensing that presently cannot be demonstrated, because of a lack of suitable fabrication methods allowing the structural control of the plasmonic atoms on a large scale. Here we demonstrate a wafer-scale “lithography-free” parallel fabrication scheme to realize nanogap plasmonic meta-molecules with precise control over their size, shape, material, and orientation. We demonstrate how we can tune the corresponding coupled resonances through the entire visible spectrum. Our fabrication method, based on glancing angle physical vapor deposition with gradient shadowing, permits critical parameters to be varied across the wafer and thus is ideally suited to screen potential structures. We obtain billions of aligned dimer structures with controlled variation of the spectral properties across the wafer. We spectroscopically map the plasmonic resonances of gold dimer structures and show that they not only are in good agreement with numerically modeled spectra, but also remain functional, at least for a year, in ambient conditions.

pf

link (url) DOI [BibTex]


Thumb xl distributed pt control
Predictive Triggering for Distributed Control of Resource Constrained Multi-agent Systems

Mastrangelo, J. M., Baumann, D., Trimpe, S.

In Proceedings of the 8th IFAC Workshop on Distributed Estimation and Control in Networked Systems, 8th IFAC Workshop on Distributed Estimation and Control in Networked Systems (NecSys), September 2019 (inproceedings)

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arXiv PDF [BibTex]

arXiv PDF [BibTex]


Thumb xl enzyme nanonets toc
Genetically modified M13 bacteriophage nanonets for enzyme catalysis and recovery

Kadiri, V. M., Alarcon-Correa, M., Guenther, J. P., Ruppert, J., Bill, J., Rothenstein, D., Fischer, P.

Catalysts, 9, pages: 723, August 2019 (article)

Abstract
Enzyme-based biocatalysis exhibits multiple advantages over inorganic catalysts, including the biocompatibility and the unchallenged specificity of enzymes towards their substrate. The recovery and repeated use of enzymes is essential for any realistic application in biotechnology, but is not easily achieved with current strategies. For this purpose, enzymes are often immobilized on inorganic scaffolds, which could entail a reduction of the enzymes’ activity. Here, we show that immobilization to a nano-scaled biological scaffold, a nanonetwork of end-to-end cross-linked M13 bacteriophages, ensures high enzymatic activity and at the same time allows for the simple recovery of the enzymes. The bacteriophages have been genetically engineered to express AviTags at their ends, which permit biotinylation and their specific end-to-end self-assembly while allowing space on the major coat protein for enzyme coupling. We demonstrate that the phages form nanonetwork structures and that these so-called nanonets remain highly active even after re-using the nanonets multiple times in a flow-through reactor.

pf

link (url) DOI [BibTex]


Thumb xl special issue adv opt mat
Light-controlled micromotors and soft microrobots

Palagi, S., Singh, D. P., Fischer, P.

Adv. Opt. Mat., 7, pages: 1900370, August 2019 (article)

Abstract
Mobile microscale devices and microrobots can be powered by catalytic reactions (chemical micromotors) or by external fields. This report is focused on the role of light as a versatile means for wirelessly powering and controlling such microdevices. Recent advances in the development of autonomous micromotors are discussed, where light permits their actuation with unprecedented control and thereby enables advances in the field of active matter. In addition, structuring the light field is a new means to drive soft microrobots that are based on (photo‐) responsive polymers. The behavior of the two main classes of thermo‐ and photoresponsive polymers adopted in microrobotics (poly(N‐isopropylacrylamide) and liquid‐crystal elastomers) is analyzed, and recent applications are reported. The advantages and limitations of controlling micromotors and microrobots by light are reviewed, and some of the remaining challenges in the development of novel photo‐active materials for micromotors and microrobots are discussed.

pf

link (url) DOI [BibTex]


Thumb xl marss 42 palagi
Soft Continuous Surface for Micromanipulation driven by Light-controlled Hydrogels

Choi, E., Jeong, H., Qiu, T., Fischer, P., Palagi, S.

4th IEEE International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), July 2019 (conference)

Abstract
Remotely controlled, automated actuation and manipulation at the microscale is essential for a number of micro-manufacturing, biology, and lab-on-a-chip applications. To transport and manipulate micro-objects, arrays of remotely controlled micro-actuators are required, which, in turn, typically require complex and expensive solid-state chips. Here, we show that a continuous surface can function as a highly parallel, many-degree of freedom, wirelessly-controlled microactuator with seamless deformation. The soft continuous surface is based on a hydrogel that undergoes a volume change in response to applied light. The fabrication of the hydrogels and the characterization of their optical and thermomechanical behaviors are reported. The temperature-dependent localized deformation of the hydrogel is also investigated by numerical simulations. Static and dynamic deformations are obtained in the soft material by projecting light fields at high spatial resolution onto the surface. By controlling such deformations in open loop and especially closed loop, automated photoactuation is achieved. The surface deformations are then exploited to examine how inert microbeads can be manipulated autonomously on the surface. We believe that the proposed approach suggests ways to implement universal 2D micromanipulation schemes that can be useful for automation in microfabrication and lab-on-a-chip applications.

pf

[BibTex]

[BibTex]


Thumb xl kindney phantom
Soft Phantom for the Training of Renal Calculi Diagnostics and Lithotripsy

Li., D., Suarez-Ibarrola, R., Choi, E., Jeong, M., Gratzke, C., Miernik, A., Fischer, P., Qiu, T.

41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), July 2019 (conference)

Abstract
Organ models are important for medical training and surgical planning. With the fast development of additive fabrication technologies, including 3D printing, the fabrication of 3D organ phantoms with precise anatomical features becomes possible. Here, we develop the first high-resolution kidney phantom based on soft material assembly, by combining 3D printing and polymer molding techniques. The phantom exhibits both the detailed anatomy of a human kidney and the elasticity of soft tissues. The phantom assembly can be separated into two parts on the coronal plane, thus large renal calculi are readily placed at any desired location of the calyx. With our sealing method, the assembled phantom withstands a hydraulic pressure that is four times the normal intrarenal pressure, thus it allows the simulation of medical procedures under realistic pressure conditions. The medical diagnostics of the renal calculi is performed by multiple imaging modalities, including X-ray, ultrasound imaging and endoscopy. The endoscopic lithotripsy is also successfully performed on the phantom. The use of a multifunctional soft phantom assembly thus shows great promise for the simulation of minimally invasive medical procedures under realistic conditions.

pf

[BibTex]

[BibTex]


Thumb xl marss qiu
A Magnetic Actuation System for the Active Microrheology in Soft Biomaterials

Jeong, M., Choi, E., Li., D., Palagi, S., Fischer, P., Qiu, T.

4th IEEE International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS), July 2019 (conference)

Abstract
Microrheology is a key technique to characterize soft materials at small scales. The microprobe is wirelessly actuated and therefore typically only low forces or torques can be applied, which limits the range of the applied strain. Here, we report a new magnetic actuation system for microrheology consisting of an array of rotating permanent magnets, which achieves a rotating magnetic field with a spatially homogeneous high field strength of ~100 mT in a working volume of ~20×20×20 mm3. Compared to a traditional electromagnetic coil system, the permanent magnet assembly is portable and does not require cooling, and it exerts a large magnetic torque on the microprobe that is an order of magnitude higher than previous setups. Experimental results demonstrate that the measurement range of the soft gels’ elasticity covers at least five orders of magnitude. With the large actuation torque, it is also possible to study the fracture mechanics of soft biomaterials at small scales.

pf

[BibTex]

[BibTex]


Thumb xl acc pulse ctrl
Event-triggered Pulse Control with Model Learning (if Necessary)

Baumann, D., Solowjow, F., Johansson, K. H., Trimpe, S.

In Proceedings of the American Control Conference, pages: 792-797, American Control Conference (ACC), July 2019 (inproceedings)

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arXiv PDF [BibTex]

arXiv PDF [BibTex]


Thumb xl pic
Data-driven inference of passivity properties via Gaussian process optimization

Romer, A., Trimpe, S., Allgöwer, F.

In Proceedings of the European Control Conference, European Control Conference (ECC), June 2019 (inproceedings)

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PDF [BibTex]

PDF [BibTex]


Thumb xl coverimage1
Trajectory-Based Off-Policy Deep Reinforcement Learning

Doerr, A., Volpp, M., Toussaint, M., Trimpe, S., Daniel, C.

In Proceedings of the International Conference on Machine Learning (ICML), International Conference on Machine Learning (ICML), June 2019 (inproceedings)

Abstract
Policy gradient methods are powerful reinforcement learning algorithms and have been demonstrated to solve many complex tasks. However, these methods are also data-inefficient, afflicted with high variance gradient estimates, and frequently get stuck in local optima. This work addresses these weaknesses by combining recent improvements in the reuse of off-policy data and exploration in parameter space with deterministic behavioral policies. The resulting objective is amenable to standard neural network optimization strategies like stochastic gradient descent or stochastic gradient Hamiltonian Monte Carlo. Incorporation of previous rollouts via importance sampling greatly improves data-efficiency, whilst stochastic optimization schemes facilitate the escape from local optima. We evaluate the proposed approach on a series of continuous control benchmark tasks. The results show that the proposed algorithm is able to successfully and reliably learn solutions using fewer system interactions than standard policy gradient methods.

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arXiv PDF [BibTex]

arXiv PDF [BibTex]


Thumb xl trimpe2019resource image
Resource-aware IoT Control: Saving Communication through Predictive Triggering

Trimpe, S., Baumann, D.

IEEE Internet of Things Journal, 6(3):5013-5028, June 2019 (article)

Abstract
The Internet of Things (IoT) interconnects multiple physical devices in large-scale networks. When the 'things' coordinate decisions and act collectively on shared information, feedback is introduced between them. Multiple feedback loops are thus closed over a shared, general-purpose network. Traditional feedback control is unsuitable for design of IoT control because it relies on high-rate periodic communication and is ignorant of the shared network resource. Therefore, recent event-based estimation methods are applied herein for resource-aware IoT control allowing agents to decide online whether communication with other agents is needed, or not. While this can reduce network traffic significantly, a severe limitation of typical event-based approaches is the need for instantaneous triggering decisions that leave no time to reallocate freed resources (e.g., communication slots), which hence remain unused. To address this problem, novel predictive and self triggering protocols are proposed herein. From a unified Bayesian decision framework, two schemes are developed: self triggers that predict, at the current triggering instant, the next one; and predictive triggers that check at every time step, whether communication will be needed at a given prediction horizon. The suitability of these triggers for feedback control is demonstrated in hardware experiments on a cart-pole, and scalability is discussed with a multi-vehicle simulation.

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PDF arXiv DOI [BibTex]

PDF arXiv DOI [BibTex]


Thumb xl testbed v5
Feedback Control Goes Wireless: Guaranteed Stability over Low-power Multi-hop Networks

(Best Paper Award)

Mager, F., Baumann, D., Jacob, R., Thiele, L., Trimpe, S., Zimmerling, M.

In Proceedings of the 10th ACM/IEEE International Conference on Cyber-Physical Systems, pages: 97-108, 10th ACM/IEEE International Conference on Cyber-Physical Systems, April 2019 (inproceedings)

Abstract
Closing feedback loops fast and over long distances is key to emerging applications; for example, robot motion control and swarm coordination require update intervals below 100 ms. Low-power wireless is preferred for its flexibility, low cost, and small form factor, especially if the devices support multi-hop communication. Thus far, however, closed-loop control over multi-hop low-power wireless has only been demonstrated for update intervals on the order of multiple seconds. This paper presents a wireless embedded system that tames imperfections impairing control performance such as jitter or packet loss, and a control design that exploits the essential properties of this system to provably guarantee closed-loop stability for linear dynamic systems. Using experiments on a testbed with multiple cart-pole systems, we are the first to demonstrate the feasibility and to assess the performance of closed-loop control and coordination over multi-hop low-power wireless for update intervals from 20 ms to 50 ms.

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arXiv PDF DOI Project Page [BibTex]

arXiv PDF DOI Project Page [BibTex]


no image
Demo Abstract: Fast Feedback Control and Coordination with Mode Changes for Wireless Cyber-Physical Systems

(Best Demo Award)

Mager, F., Baumann, D., Jacob, R., Thiele, L., Trimpe, S., Zimmerling, M.

Proceedings of the 18th ACM/IEEE Conference on Information Processing in Sensor Networks (IPSN), pages: 340-341, 18th ACM/IEEE Conference on Information Processing in Sensor Networks (IPSN), April 2019 (poster)

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arXiv PDF DOI [BibTex]

arXiv PDF DOI [BibTex]


Thumb xl m13 bacteriophages
Self-Assembled Phage-Based Colloids for High Localized Enzymatic Activity

Alarcon-Correa, M., Guenther, J., Troll, J., Kadiri, V. M., Bill, J., Fischer, P., Rothenstein, D.

ACS Nano, March 2019 (article)

Abstract
Catalytically active colloids are model systems for chemical motors and active matter. It is desirable to replace the inorganic catalysts and the toxic fuels that are often used, with biocompatible enzymatic reactions. However, compared to inorganic catalysts, enzyme-coated colloids tend to exhibit less activity. Here, we show that the self-assembly of genetically engineered M13 bacteriophages that bind enzymes to magnetic beads ensures high and localized enzymatic activity. These phage-decorated colloids provide a proteinaceous environment for directed enzyme immobilization. The magnetic properties of the colloidal carrier particle permit repeated enzyme recovery from a reaction solution, while the enzymatic activity is retained. Moreover, localizing the phage-based construct with a magnetic field in a microcontainer allows the enzyme-phage-colloids to function as an enzymatic micropump, where the enzymatic reaction generates a fluid flow. This system shows the fastest fluid flow reported to date by a biocompatible enzymatic micropump. In addition, it is functional in complex media including blood where the enzyme driven micropump can be powered at the physiological blood-urea concentration.

pf

link (url) DOI [BibTex]


Thumb xl jcp pfg nmr
Absolute diffusion measurements of active enzyme solutions by NMR

Guenther, J., Majer, G., Fischer, P.

J. Chem. Phys., 150(124201), March 2019 (article)

Abstract
The diffusion of enzymes is of fundamental importance for many biochemical processes. Enhanced or directed enzyme diffusion can alter the accessibility of substrates and the organization of enzymes within cells. Several studies based on fluorescence correlation spectroscopy (FCS) report enhanced diffusion of enzymes upon interaction with their substrate or inhibitor. In this context, major importance is given to the enzyme fructose-bisphosphate aldolase, for which enhanced diffusion has been reported even though the catalysed reaction is endothermic. Additionally, enhanced diffusion of tracer particles surrounding the active aldolase enzymes has been reported. These studies suggest that active enzymes can act as chemical motors that self-propel and give rise to enhanced diffusion. However, fluorescence studies of enzymes can, despite several advantages, suffer from artefacts. Here we show that the absolute diffusion coefficients of active enzyme solutions can be determined with Pulsed Field Gradient Nuclear Magnetic Resonance (PFG-NMR). The advantage of PFG-NMR is that the motion of the molecule of interest is directly observed in its native state without the need for any labelling. Further, PFG-NMR is model-free and thus yields absolute diffusion constants. Our PFG-NMR experiments of solutions containing active fructose-bisphosphate aldolase from rabbit muscle do not show any diffusion enhancement for the active enzymes nor the surrounding molecules. Additionally, we do not observe any diffusion enhancement of aldolase in the presence of its inhibitor pyrophosphate.

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link (url) DOI [BibTex]


Thumb xl activeoptorheologicalmedium
Chemical Nanomotors at the Gram Scale Form a Dense Active Optorheological Medium

Choudhury, U., Singh, D. P., Qiu, T., Fischer, P.

Adv. Mat., (1807382), Febuary 2019 (article)

Abstract
The rheological properties of a colloidal suspension are a function of the concentration of the colloids and their interactions. While suspensions of passive colloids are well studied and have been shown to form crystals, gels, and glasses, examples of energy‐consuming “active” colloidal suspensions are still largely unexplored. Active suspensions of biological matter, such as motile bacteria or dense mixtures of active actin–motor–protein mixtures have, respectively, reveals superfluid‐like and gel‐like states. Attractive inanimate systems for active matter are chemically self‐propelled particles. It has so far been challenging to use these swimming particles at high enough densities to affect the bulk material properties of the suspension. Here, it is shown that light‐triggered asymmetric titanium dioxide that self‐propel, can be obtained in large quantities, and self‐organize to make a gram‐scale active medium. The suspension shows an activity‐dependent tenfold reversible change in its bulk viscosity.

pf

link (url) DOI [BibTex]


Thumb xl lic overview
Fast and Resource-Efficient Control of Wireless Cyber-Physical Systems

Baumann, D.

KTH Royal Institute of Technology, Stockholm, Febuary 2019 (phdthesis)

ics

PDF [BibTex]

PDF [BibTex]


Thumb xl hyperrayleigh
First Observation of Optical Activity in Hyper-Rayleigh Scattering

Collins, J., Rusimova, K., Hooper, D., Jeong, H. H., Ohnoutek, L., Pradaux-Caggiano, F., Verbiest, T., Carbery, D., Fischer, P., Valev, V.

Phys. Rev. X, 9(011024), January 2019 (article)

Abstract
Chiral nano- or metamaterials and surfaces enable striking photonic properties, such as negative refractive index and superchiral light, driving promising applications in novel optical components, nanorobotics, and enhanced chiral molecular interactions with light. In characterizing chirality, although nonlinear chiroptical techniques are typically much more sensitive than their linear optical counterparts, separating true chirality from anisotropy is a major challenge. Here, we report the first observation of optical activity in second-harmonic hyper-Rayleigh scattering (HRS). We demonstrate the effect in a 3D isotropic suspension of Ag nanohelices in water. The effect is 5 orders of magnitude stronger than linear optical activity and is well pronounced above the multiphoton luminescence background. Because of its sensitivity, isotropic environment, and straightforward experimental geometry, HRS optical activity constitutes a fundamental experimental breakthrough in chiral photonics for media including nanomaterials, metamaterials, and chemical molecules.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


Thumb xl journal iav
Data-efficient Auto-tuning with Bayesian Optimization: An Industrial Control Study

Neumann-Brosig, M., Marco, A., Schwarzmann, D., Trimpe, S.

IEEE Transactions on Control Systems Technology, 2019 (article) Accepted

Abstract
Bayesian optimization is proposed for automatic learning of optimal controller parameters from experimental data. A probabilistic description (a Gaussian process) is used to model the unknown function from controller parameters to a user-defined cost. The probabilistic model is updated with data, which is obtained by testing a set of parameters on the physical system and evaluating the cost. In order to learn fast, the Bayesian optimization algorithm selects the next parameters to evaluate in a systematic way, for example, by maximizing information gain about the optimum. The algorithm thus iteratively finds the globally optimal parameters with only few experiments. Taking throttle valve control as a representative industrial control example, the proposed auto-tuning method is shown to outperform manual calibration: it consistently achieves better performance with a low number of experiments. The proposed auto-tuning framework is flexible and can handle different control structures and objectives.

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arXiv (PDF) DOI Project Page [BibTex]

arXiv (PDF) DOI Project Page [BibTex]


Thumb xl blockdiag
Event-triggered Learning

Solowjow, F., Trimpe, S.

2019 (techreport) Submitted

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arXiv PDF [BibTex]


no image
Robust Humanoid Locomotion Using Trajectory Optimization and Sample-Efficient Learning

Yeganegi, M. H., Khadiv, M., Moosavian, S. A. A., Zhu, J., Prete, A. D., Righetti, L.

Proceedings International Conference on Humanoid Robots, IEEE, 2019 IEEE-RAS International Conference on Humanoid Robots, 2019 (conference)

Abstract
Trajectory optimization (TO) is one of the most powerful tools for generating feasible motions for humanoid robots. However, including uncertainties and stochasticity in the TO problem to generate robust motions can easily lead to intractable problems. Furthermore, since the models used in TO have always some level of abstraction, it can be hard to find a realistic set of uncertainties in the model space. In this paper we leverage a sample-efficient learning technique (Bayesian optimization) to robustify TO for humanoid locomotion. The main idea is to use data from full-body simulations to make the TO stage robust by tuning the cost weights. To this end, we split the TO problem into two phases. The first phase solves a convex optimization problem for generating center of mass (CoM) trajectories based on simplified linear dynamics. The second stage employs iterative Linear-Quadratic Gaussian (iLQG) as a whole-body controller to generate full body control inputs. Then we use Bayesian optimization to find the cost weights to use in the first stage that yields robust performance in the simulation/experiment, in the presence of different disturbance/uncertainties. The results show that the proposed approach is able to generate robust motions for different sets of disturbances and uncertainties.

mg

https://arxiv.org/abs/1907.04616 [BibTex]

https://arxiv.org/abs/1907.04616 [BibTex]

2011


Thumb xl toc image
Quantum-Cascade Laser-Based Vibrational Circular Dichroism

Luedeke, S., Pfeifer, M., Fischer, P.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(15):5704-5707, 2011 (article)

Abstract
Vibrational circular dichroism (VCD) spectra were recorded with a tunable external-cavity quantum-cascade laser (QCL). In comparison with standard thermal light sources in the IR, QCLs provide orders of magnitude more power and are therefore promising for VCD studies in strongly absorbing solvents. The brightness of this novel light source is demonstrated with VCD and IR absorption measurements of a number of compounds, including proline in water.

pf

DOI [BibTex]

2011


DOI [BibTex]


Thumb xl toc image
Actively coupled cavity ringdown spectroscopy with low-power broadband sources

Petermann, C., Fischer, P.

OPTICS EXPRESS, 19(11):10164-10173, 2011 (article)

Abstract
We demonstrate a coupling scheme for cavity enhanced absorption spectroscopy that makes use of an intracavity acousto-optical modulator to actively switch light into (and out of) a resonator. This allows cavity ringdown spectroscopy (CRDS) to be implemented with broadband nonlaser light sources with spectral power densities of less than 30 mu W/nm. Although the acousto-optical element reduces the ultimate detection limit by introducing additional losses, it permits absorptivities to be measured with a high dynamic range, especially in lossy environments. Absorption measurements for the forbidden transition of gaseous oxygen in air at similar to 760nm are presented using a low-coherence cw-superluminescent diode. The same setup was electronically configured to cover absorption losses from 1.8 x 10(-8)cm(-1) to 7.5\% per roundtrip. This could be of interest in process analytical applications. (C) 2011 Optical Society of America

pf

DOI [BibTex]

DOI [BibTex]


Thumb xl toc image
Magnetically actuated propulsion at low Reynolds numbers: towards nanoscale control

Fischer, P., Ghosh, A.

NANOSCALE, 3(2):557-563, 2011 (article)

Abstract
Significant progress has been made in the fabrication of micron and sub-micron structures whose motion can be controlled in liquids under ambient conditions. The aim of many of these engineering endeavors is to be able to build and propel an artificial micro-structure that rivals the versatility of biological swimmers of similar size, e. g. motile bacterial cells. Applications for such artificial ``micro-bots'' are envisioned to range from microrheology to targeted drug delivery and microsurgery, and require full motion-control under ambient conditions. In this Mini-Review we discuss the construction, actuation, and operation of several devices that have recently been reported, especially systems that can be controlled by and propelled with homogenous magnetic fields. We describe the fabrication and associated experimental challenges and discuss potential applications.

pf

Video - Nanospropellers DOI [BibTex]


Thumb xl toc image
Weak value amplified optical activity measurements

Pfeifer, M., Fischer, P.

Opt. Express, 19(17):16508-16517, OSA, 2011 (article)

Abstract
We present a new form of optical activity measurement based on a modified weak value amplification scheme. It has recently been shown experimentally that the left- and right-circular polarization components refract with slightly different angles of refraction at a chiral interface causing a linearly polarized light beam to split into two. By introducing a polarization modulation that does not give rise to a change in the optical rotation it is possible to differentiate between the two circular polarization components even after post-selection with a linear polarizer. We show that such a modified weak value amplification measurement permits the sign of the splitting and thus the handedness of the optically active medium to be determined. Angular beam separations of Δθ ∼ 1 nanoradian, which corresponds to a circular birefringence of Δn ∼ 1 × 10−9, could be measured with a relative error of less than 1%.

pf

link (url) DOI [BibTex]

link (url) DOI [BibTex]


no image
Toward simple control for complex, autonomous robotic applications: combining discrete and rhythmic motor primitives

Degallier, S., Righetti, L., Gay, S., Ijspeert, A.

Autonomous Robots, 31(2-3):155-181, October 2011 (article)

Abstract
Vertebrates are able to quickly adapt to new environments in a very robust, seemingly effortless way. To explain both this adaptivity and robustness, a very promising perspective in neurosciences is the modular approach to movement generation: Movements results from combinations of a finite set of stable motor primitives organized at the spinal level. In this article we apply this concept of modular generation of movements to the control of robots with a high number of degrees of freedom, an issue that is challenging notably because planning complex, multidimensional trajectories in time-varying environments is a laborious and costly process. We thus propose to decrease the complexity of the planning phase through the use of a combination of discrete and rhythmic motor primitives, leading to the decoupling of the planning phase (i.e. the choice of behavior) and the actual trajectory generation. Such implementation eases the control of, and the switch between, different behaviors by reducing the dimensionality of the high-level commands. Moreover, since the motor primitives are generated by dynamical systems, the trajectories can be smoothly modulated, either by high-level commands to change the current behavior or by sensory feedback information to adapt to environmental constraints. In order to show the generality of our approach, we apply the framework to interactive drumming and infant crawling in a humanoid robot. These experiments illustrate the simplicity of the control architecture in terms of planning, the integration of different types of feedback (vision and contact) and the capacity of autonomously switching between different behaviors (crawling and simple reaching).

mg

link (url) DOI [BibTex]

link (url) DOI [BibTex]


no image
Learning Force Control Policies for Compliant Manipulation

Kalakrishnan, M., Righetti, L., Pastor, P., Schaal, S.

In 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems, pages: 4639-4644, IEEE, San Francisco, USA, sep 2011 (inproceedings)

Abstract
Developing robots capable of fine manipulation skills is of major importance in order to build truly assistive robots. These robots need to be compliant in their actuation and control in order to operate safely in human environments. Manipulation tasks imply complex contact interactions with the external world, and involve reasoning about the forces and torques to be applied. Planning under contact conditions is usually impractical due to computational complexity, and a lack of precise dynamics models of the environment. We present an approach to acquiring manipulation skills on compliant robots through reinforcement learning. The initial position control policy for manipulation is initialized through kinesthetic demonstration. We augment this policy with a force/torque profile to be controlled in combination with the position trajectories. We use the Policy Improvement with Path Integrals (PI2) algorithm to learn these force/torque profiles by optimizing a cost function that measures task success. We demonstrate our approach on the Barrett WAM robot arm equipped with a 6-DOF force/torque sensor on two different manipulation tasks: opening a door with a lever door handle, and picking up a pen off the table. We show that the learnt force control policies allow successful, robust execution of the tasks.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Control of legged robots with optimal distribution of contact forces

Righetti, L., Buchli, J., Mistry, M., Schaal, S.

In 2011 11th IEEE-RAS International Conference on Humanoid Robots, pages: 318-324, IEEE, Bled, Slovenia, 2011 (inproceedings)

Abstract
The development of agile and safe humanoid robots require controllers that guarantee both high tracking performance and compliance with the environment. More specifically, the control of contact interaction is of crucial importance for robots that will actively interact with their environment. Model-based controllers such as inverse dynamics or operational space control are very appealing as they offer both high tracking performance and compliance. However, while widely used for fully actuated systems such as manipulators, they are not yet standard controllers for legged robots such as humanoids. Indeed such robots are fundamentally different from manipulators as they are underactuated due to their floating-base and subject to switching contact constraints. In this paper we present an inverse dynamics controller for legged robots that use torque redundancy to create an optimal distribution of contact constraints. The resulting controller is able to minimize, given a desired motion, any quadratic cost of the contact constraints at each instant of time. In particular we show how this can be used to minimize tangential forces during locomotion, therefore significantly improving the locomotion of legged robots on difficult terrains. In addition to the theoretical result, we present simulations of a humanoid and a quadruped robot, as well as experiments on a real quadruped robot that demonstrate the advantages of the controller.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Learning Motion Primitive Goals for Robust Manipulation

Stulp, F., Theodorou, E., Kalakrishnan, M., Pastor, P., Righetti, L., Schaal, S.

In IEEE/RSJ International Conference on Intelligent Robots and Systems, pages: 325-331, IEEE, San Francisco, USA, sep 2011 (inproceedings)

Abstract
Applying model-free reinforcement learning to manipulation remains challenging for several reasons. First, manipulation involves physical contact, which causes discontinuous cost functions. Second, in manipulation, the end-point of the movement must be chosen carefully, as it represents a grasp which must be adapted to the pose and shape of the object. Finally, there is uncertainty in the object pose, and even the most carefully planned movement may fail if the object is not at the expected position. To address these challenges we 1) present a simplified, computationally more efficient version of our model-free reinforcement learning algorithm PI2; 2) extend PI2 so that it simultaneously learns shape parameters and goal parameters of motion primitives; 3) use shape and goal learning to acquire motion primitives that are robust to object pose uncertainty. We evaluate these contributions on a manipulation platform consisting of a 7-DOF arm with a 4-DOF hand.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Inverse Dynamics Control of Floating-Base Robots with External Constraints: a Unified View

Righetti, L., Buchli, J., Mistry, M., Schaal, S.

In 2011 IEEE International Conference on Robotics and Automation, pages: 1085-1090, IEEE, Shanghai, China, 2011 (inproceedings)

Abstract
Inverse dynamics controllers and operational space controllers have proved to be very efficient for compliant control of fully actuated robots such as fixed base manipulators. However legged robots such as humanoids are inherently different as they are underactuated and subject to switching external contact constraints. Recently several methods have been proposed to create inverse dynamics controllers and operational space controllers for these robots. In an attempt to compare these different approaches, we develop a general framework for inverse dynamics control and show that these methods lead to very similar controllers. We are then able to greatly simplify recent whole-body controllers based on operational space approaches using kinematic projections, bringing them closer to efficient practical implementations. We also generalize these controllers such that they can be optimal under an arbitrary quadratic cost in the commands.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Operational Space Control of Constrained and Underactuated Systems

Mistry, M., Righetti, L.

In Proceedings of Robotics: Science and Systems, Los Angeles, CA, USA, June 2011 (inproceedings)

Abstract
The operational space formulation (Khatib, 1987), applied to rigid-body manipulators, describes how to decouple task-space and null-space dynamics, and write control equations that correspond only to forces at the end-effector or, alternatively, only to motion within the null-space. We would like to apply this useful theory to modern humanoids and other legged systems, for manipulation or similar tasks, however these systems present additional challenges due to their underactuated floating bases and contact states that can dynamically change. In recent work, Sentis et al. derived controllers for such systems by implementing a task Jacobian projected into a space consistent with the supporting constraints and underactuation (the so called "support consistent reduced Jacobian"). Here, we take a new approach to derive operational space controllers for constrained underactuated systems, by first considering the operational space dynamics within "projected inverse-dynamics" (Aghili, 2005), and subsequently resolving underactuation through the addition of dynamically consistent control torques. Doing so results in a simplified control solution compared with previous results, and importantly yields several new insights into the underlying problem of operational space control in constrained environments: 1) Underactuated systems, such as humanoid robots, cannot in general completely decouple task and null-space dynamics. However, 2) there may exist an infinite number of control solutions to realize desired task-space dynamics, and 3) these solutions involve the addition of dynamically consistent null-space motion or constraint forces (or combinations of both). In light of these findings, we present several possible control solutions, with varying optimization criteria, and highlight some of their practical consequences.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Online movement adaptation based on previous sensor experiences

Pastor, P., Righetti, L., Kalakrishnan, M., Schaal, S.

In 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems, pages: 365-371, IEEE, San Francisco, USA, sep 2011 (inproceedings)

Abstract
Personal robots can only become widespread if they are capable of safely operating among humans. In uncertain and highly dynamic environments such as human households, robots need to be able to instantly adapt their behavior to unforseen events. In this paper, we propose a general framework to achieve very contact-reactive motions for robotic grasping and manipulation. Associating stereotypical movements to particular tasks enables our system to use previous sensor experiences as a predictive model for subsequent task executions. We use dynamical systems, named Dynamic Movement Primitives (DMPs), to learn goal-directed behaviors from demonstration. We exploit their dynamic properties by coupling them with the measured and predicted sensor traces. This feedback loop allows for online adaptation of the movement plan. Our system can create a rich set of possible motions that account for external perturbations and perception uncertainty to generate truly robust behaviors. As an example, we present an application to grasping with the WAM robot arm.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Nonlinear optical spectroscopy of chiral molecules

Fischer, P., Hache, F.

CHIRALITY, 17(8):421-437, 2005 (article)

Abstract
We review nonlinear optical processes that are specific to chiral molecules in solution and on surfaces. In contrast to conventional natural optical activity phenomena, which depend linearly on the electric field strength of the optical field, we discuss how optical processes that are nonlinear (quadratic, cubic, and quartic) functions of the electromagnetic field strength may probe optically active centers and chiral vibrations. We show that nonlinear techniques open entirely new ways of exploring chirality in chemical and biological systems: The cubic processes give rise to nonlinear circular dichroism and nonlinear optical rotation and make it possible to observe dynamic chiral processes at ultrafast time scales. The quadratic second-harmonic and sum-frequency-generation phenomena and the quartic processes may arise entirely in the electric-dipole approximation and do not require the use of circularly polarized light to detect chirality: They provide surface selectivity and their observables can be relatively much larger than in linear optical activity. These processes also give rise to the generation of light at a new color, and in liquids this frequency conversion only occurs if the solution is optically active. We survey recent chiral nonlinear optical experiments and give examples of their application to problems of biophysical interest. (C) 2005 Wiley-Liss, Inc.

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DOI [BibTex]

DOI [BibTex]


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Negative refraction at optical frequencies in nonmagnetic two-component molecular media

Chen, Y., Fischer, P., Wise, F.

PHYSICAL REVIEW LETTERS, 95(6), 2005 (article)

Abstract
There is significant motivation to develop media with negative refractive indices at optical frequencies, but efforts in this direction are hampered by the weakness of the magnetic response at such frequencies. We show theoretically that a nonmagnetic medium with two atomic or molecular constituents can exhibit a negative refractive index. A negative index is possible even when the real parts of both the permittivity and permeability are positive. This surprising result provides a route to isotropic negative-index media at optical frequencies.

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DOI [BibTex]

DOI [BibTex]


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A dynamical systems approach to learning: a frequency-adaptive hopper robot

Buchli, J., Righetti, L., Ijspeert, A.

In Proceedings of the VIIIth European Conference on Artificial Life ECAL 2005, pages: 210-220, Springer Verlag, 2005 (inproceedings)

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[BibTex]

[BibTex]


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From Dynamic Hebbian Learning for Oscillators to Adaptive Central Pattern Generators

Righetti, L., Buchli, J., Ijspeert, A.

In Proceedings of 3rd International Symposium on Adaptive Motion in Animals and Machines – AMAM 2005, Verlag ISLE, Ilmenau, 2005 (inproceedings)

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[BibTex]

[BibTex]