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2004


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E. Coli Inspired Propulsion for Swimming Microrobots

Behkam, Bahareh, Sitti, Metin

pages: 1037–1041, 2004 (article)

Abstract
Medical applications are among the most fascinating areas of microrobotics. For long, scientists have dreamed of miniature smart devices that can travel inside the human body and carry out a host of complex operations such as minimally invasive surgery (MIS), highly localized drug delivery, and screening for diseases that are in their very early stages. Still a distant dream, significant progress in micro and nanotechnology brings us closer to materializing it. For such a miniature device to be injected into the body, it has to be 800 μm or smaller in diameter. Miniature, safe and energy efficient propulsion systems hold the key to maturing this technology but they pose significant challenges. Scaling the macroscale natation mechanisms to micro/nano length scales is unfeasible. It has been estimated that a vibrating-fin driven swimming robot shorter than 6 mm can not overcome the viscous drag forces in water. In this paper, the authors propose a new type of propulsion inspired by the motility mechanism of bacteria with peritrichous flagellation, such as Escherichia coli, Salmonella typhimurium and Serratia marcescens. The perfomance of the propulsive mechanism is estimated by modeling the dynamics of the motion. The motion of the moving organelle is simulated and key parameters such as velocity, distribution of force and power requirments for different configurations of the tail are determined theoretically. In order to validate the theoretical result, a scaled up model of the swimming robot is fabricated and characterized in silicone oil using the Buckingham PI theorem for scaling. The results are compared with the theoretically computed values. These robots are intended to swim in stagnation/low velocity biofluid and reach currently inaccessible areas of the human body for disease inspection and possibly treatment. Potential target regions to use these robots include eyeball cavity, cerebrospinal fluid and the urinary system.

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link (url) DOI [BibTex]

2004


link (url) DOI [BibTex]


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Discovering optimal imitation strategies

Billard, A., Epars, Y., Calinon, S., Cheng, G., Schaal, S.

Robotics and Autonomous Systems, 47(2-3):68-77, 2004, clmc (article)

Abstract
This paper develops a general policy for learning relevant features of an imitation task. We restrict our study to imitation of manipulative tasks or of gestures. The imitation process is modeled as a hierarchical optimization system, which minimizes the discrepancy between two multi-dimensional datasets. To classify across manipulation strategies, we apply a probabilistic analysis to data in Cartesian and joint spaces. We determine a general metric that optimizes the policy of task reproduction, following strategy determination. The model successfully discovers strategies in six different imitative tasks and controls task reproduction by a full body humanoid robot.

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[BibTex]

[BibTex]


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Rhythmic movement is not discrete

Schaal, S., Sternad, D., Osu, R., Kawato, M.

Nature Neuroscience, 7(10):1137-1144, 2004, clmc (article)

Abstract
Rhythmic movements, like walking, chewing, or scratching, are phylogenetically old mo-tor behaviors found in many organisms, ranging from insects to primates. In contrast, discrete movements, like reaching, grasping, or kicking, are behaviors that have reached sophistication primarily in younger species, particularly in primates. Neurophysiological and computational research on arm motor control has focused almost exclusively on dis-crete movements, essentially assuming similar neural circuitry for rhythmic tasks. In con-trast, many behavioral studies focused on rhythmic models, subsuming discrete move-ment as a special case. Here, using a human functional neuroimaging experiment, we show that in addition to areas activated in rhythmic movement, discrete movement in-volves several higher cortical planning areas, despite both movement conditions were confined to the same single wrist joint. These results provide the first neuroscientific evi-dence that rhythmic arm movement cannot be part of a more general discrete movement system, and may require separate neurophysiological and theoretical treatment.

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link (url) [BibTex]

link (url) [BibTex]


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Learning from demonstration and adaptation of biped locomotion

Nakanishi, J., Morimoto, J., Endo, G., Cheng, G., Schaal, S., Kawato, M.

Robotics and Autonomous Systems, 47(2-3):79-91, 2004, clmc (article)

Abstract
In this paper, we introduce a framework for learning biped locomotion using dynamical movement primitives based on non-linear oscillators. Our ultimate goal is to establish a design principle of a controller in order to achieve natural human-like locomotion. We suggest dynamical movement primitives as a central pattern generator (CPG) of a biped robot, an approach we have previously proposed for learning and encoding complex human movements. Demonstrated trajectories are learned through movement primitives by locally weighted regression, and the frequency of the learned trajectories is adjusted automatically by a novel frequency adaptation algorithmbased on phase resetting and entrainment of coupled oscillators. Numerical simulations and experimental implementation on a physical robot demonstrate the effectiveness of the proposed locomotioncontroller.

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link (url) [BibTex]

link (url) [BibTex]


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Atomic force microscope probe based controlled pushing for nanotribological characterization

Sitti, M.

IEEE/ASME Transactions on mechatronics, 9(2):343-349, IEEE, 2004 (article)

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[BibTex]

[BibTex]


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Feedback error learning and nonlinear adaptive control

Nakanishi, J., Schaal, S.

Neural Networks, 17(10):1453-1465, 2004, clmc (article)

Abstract
In this paper, we present our theoretical investigations of the technique of feedback error learning (FEL) from the viewpoint of adaptive control. We first discuss the relationship between FEL and nonlinear adaptive control with adaptive feedback linearization, and show that FEL can be interpreted as a form of nonlinear adaptive control. Second, we present a Lyapunov analysis suggesting that the condition of strictly positive realness (SPR) associated with the tracking error dynamics is a sufficient condition for asymptotic stability of the closed-loop dynamics. Specifically, for a class of second order SISO systems, we show that this condition reduces to KD^2 > KP; where KP and KD are positive position and velocity feedback gains, respectively. Moreover, we provide a ÔpassivityÕ-based stability analysis which suggests that SPR of the tracking error dynamics is a necessary and sufficient condition for asymptotic hyperstability. Thus, the condition KD^2>KP mentioned above is not only a sufficient but also necessary condition to guarantee asymptotic hyperstability of FEL, i.e. the tracking error is bounded and asymptotically converges to zero. As a further point, we explore the adaptive control and FEL framework for feedforward control formulations, and derive an additional sufficient condition for asymptotic stability in the sense of Lyapunov. Finally, we present numerical simulations to illustrate the stability properties of FEL obtained from our mathematical analysis.

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link (url) [BibTex]

link (url) [BibTex]

2003


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Synthetic gecko foot-hair micro/nano-structures as dry adhesives

Sitti, M., Fearing, R. S.

Journal of adhesion science and technology, 17(8):1055-1073, Taylor & Francis Group, 2003 (article)

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Project Page [BibTex]

2003


Project Page [BibTex]


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Teleoperated touch feedback from the surfaces at the nanoscale: modeling and experiments

Sitti, M., Hashimoto, H.

IEEE/ASME transactions on mechatronics, 8(2):287-298, IEEE, 2003 (article)

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[BibTex]

[BibTex]


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Scaled teleoperation system for nano-scale interaction and manipulation

Sitti, M., Aruk, B., Shintani, H., Hashimoto, H.

Advanced Robotics, 17(3):275-291, Taylor & Francis Group, 2003 (article)

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[BibTex]

[BibTex]


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Atomic force microscope probe based controlled pushing for nano-tribological characterization

Sitti, M.

IEEE/ASME Transactions on Mechatronics, 8(3), 2003 (article)

pi

[BibTex]


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Computational approaches to motor learning by imitation

Schaal, S., Ijspeert, A., Billard, A.

Philosophical Transaction of the Royal Society of London: Series B, Biological Sciences, 358(1431):537-547, 2003, clmc (article)

Abstract
Movement imitation requires a complex set of mechanisms that map an observed movement of a teacher onto one's own movement apparatus. Relevant problems include movement recognition, pose estimation, pose tracking, body correspondence, coordinate transformation from external to egocentric space, matching of observed against previously learned movement, resolution of redundant degrees-of-freedom that are unconstrained by the observation, suitable movement representations for imitation, modularization of motor control, etc. All of these topics by themselves are active research problems in computational and neurobiological sciences, such that their combination into a complete imitation system remains a daunting undertaking - indeed, one could argue that we need to understand the complete perception-action loop. As a strategy to untangle the complexity of imitation, this paper will examine imitation purely from a computational point of view, i.e. we will review statistical and mathematical approaches that have been suggested for tackling parts of the imitation problem, and discuss their merits, disadvantages and underlying principles. Given the focus on action recognition of other contributions in this special issue, this paper will primarily emphasize the motor side of imitation, assuming that a perceptual system has already identified important features of a demonstrated movement and created their corresponding spatial information. Based on the formalization of motor control in terms of control policies and their associated performance criteria, useful taxonomies of imitation learning can be generated that clarify different approaches and future research directions.

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link (url) [BibTex]

link (url) [BibTex]


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Efficient charge recovery method for driving piezoelectric actuators with quasi-square waves

Campolo, D., Sitti, M., Fearing, R. S.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 50(3):237-244, IEEE, 2003 (article)

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[BibTex]

[BibTex]


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Piezoelectrically actuated four-bar mechanism with two flexible links for micromechanical flying insect thorax

Sitti, M.

IEEE/ASME transactions on mechatronics, 8(1):26-36, IEEE, 2003 (article)

pi

[BibTex]

1995


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Memory-based neural networks for robot learning

Atkeson, C. G., Schaal, S.

Neurocomputing, 9, pages: 1-27, 1995, clmc (article)

Abstract
This paper explores a memory-based approach to robot learning, using memory-based neural networks to learn models of the task to be performed. Steinbuch and Taylor presented neural network designs to explicitly store training data and do nearest neighbor lookup in the early 1960s. In this paper their nearest neighbor network is augmented with a local model network, which fits a local model to a set of nearest neighbors. This network design is equivalent to a statistical approach known as locally weighted regression, in which a local model is formed to answer each query, using a weighted regression in which nearby points (similar experiences) are weighted more than distant points (less relevant experiences). We illustrate this approach by describing how it has been used to enable a robot to learn a difficult juggling task. Keywords: memory-based, robot learning, locally weighted regression, nearest neighbor, local models.

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link (url) [BibTex]

1995


link (url) [BibTex]


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In vivo diabetic wound healing with nanofibrous scaffolds modified with gentamicin and recombinant human epidermal growth factor

Dwivedi, C., Pandey, I., Pandey, H., Patil, S., Mishra, S. B., Pandey, A. C., Zamboni, P., Ramteke, P. W., Singh, A. V.

Journal of Biomedical Materials Research Part A, 106(3):641-651, March (article)

Abstract
Abstract Diabetic wounds are susceptible to microbial infection. The treatment of these wounds requires a higher payload of growth factors. With this in mind, the strategy for this study was to utilize a novel payload comprising of Eudragit RL/RS 100 nanofibers carrying the bacterial inhibitor gentamicin sulfate (GS) in concert with recombinant human epidermal growth factor (rhEGF); an accelerator of wound healing. GS containing Eudragit was electrospun to yield nanofiber scaffolds, which were further modified by covalent immobilization of rhEGF to their surface. This novel fabricated nanoscaffold was characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, and X‐ray diffraction. The thermal behavior of the nanoscaffold was determined using thermogravimetric analysis and differential scanning calorimetry. In the in vitro antibacterial assays, the nanoscaffolds exhibited comparable antibacterial activity to pure gentemicin powder. In vivo work using female C57/BL6 mice, the nanoscaffolds induced faster wound healing activity in dorsal wounds compared to the control. The paradigm in this study presents a robust in vivo model to enhance the applicability of drug delivery systems in wound healing applications. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 641–651, 2018.

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link (url) DOI [BibTex]


link (url) DOI [BibTex]


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Robotics Research

Tong, Chi Hay, Furgale, Paul, Barfoot, Timothy D, Guizilini, Vitor, Ramos, Fabio, Chen, Yushan, T\uumová, Jana, Ulusoy, Alphan, Belta, Calin, Tenorth, Moritz, others

(article)

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[BibTex]

[BibTex]